RecruitingNot ApplicableNCT04690439

Photobiomodulation Therapy for the Management of Breast Cancer-related Lymphedema

Evaluating the Effectiveness of Photobiomodulation Therapy in the Management of Breast Cancer-Related Lymphedema: a Randomized Controlled Trial


Sponsor

Jessa Hospital

Enrollment

104 participants

Start Date

Feb 22, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Up to one out of five patients with breast cancer will develop lymphedema in the upper extremity after cancer treatment. Patients with breast cancer-related lymphedema (BCRL) suffer from pain, heaviness, tightness, and a decreased range of motion. Photobiomodulation therapy (PBMT) is a non-invasive therapy based on the application of visible and/or near-infrared light produced by a laser diode or a light-emitting diode. The scientifically proven biologic effects of PBM are improved wound healing, and a reduction in pain, inflammation, and oedema. Therefore, the aim of this study is to evaluate the effectiveness of PBMT on the management of BCRL.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether photobiomodulation therapy (low-level light therapy using a special device) can help treat lymphedema — painful arm swelling — that develops in breast cancer survivors after surgery and radiation removed or damaged lymph nodes. **You may be eligible if...** - You have been diagnosed with breast cancer - You had a lumpectomy or mastectomy plus lymph node surgery (sentinel biopsy and/or full dissection) - You received radiation therapy (with or without chemotherapy) - You have been diagnosed with breast cancer-related lymphedema (stage I or higher) - You are 18 or older **You may NOT be eligible if...** - Your breast cancer has spread to other parts of your body (metastatic) - You are pregnant - You have had prior surgery or trauma to the affected arm - You have had an arm infection in the past 3 months - You take medications that affect body fluid (like diuretics) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEPhotobiomodulation therapy (PBMT)

The MLS M6 laser from ASA will be used to apply the laser therapy.

PROCEDUREManual Lymphatic drainage

Patients will receive twice weekly MLT executed by trained physiotherapist


Locations(2)

Hasselt University

Hasselt, Limburg, Belgium

Jessa Ziekenhuis

Hasselt, Limburg, Belgium

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NCT04690439


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