RecruitingNCT04695028

CRYSTALILLE Cohort: Getting the Whole Picture of Crystal-related Arthropathies

Data Collection for the Constitution of an Observatory for Patients Suffering From Microcrystalline Rheumatism With Morphological Phenotyping

Sponsor

Lille Catholic University

Enrollment

1,000 participants

Start Date

Mar 16, 2021

Study Type

OBSERVATIONAL

Conditions

Gout Chondrocalcinosis Hydroxyapatite

Summary

The objective of this research is to collect data to create an observatory of microcrystalline rheumatism (gout and calcium-crystal rheumatism) in patients treated at the Groupement des Hôpitaux de l'Institut Catholique de Lille, in order to better understand the disease and improve patient care, in particular with the help of medical imaging.

Eligibility

Min Age: 18 Years

Inclusion Criteria3

Diagnosis of gout according to American College of Rheumatology /European League Against Rheumatism (ACR/EULAR) 2015 criteria OR diagnosis of calcium pyrophosphate dihydrate crystal deposition disease (CPPD) based on EULAR 2011 recommendations OR diagnosis of hydroxyapatite crystal rheumatism (HCR) according to a typical clinical sequence and demonstration of compatible calcium deposits on imaging
patient who will benefit or has benefited from an ultrasound and/or DECT evaluation of microcrystalline deposits
clinical suspicion of microcrystalline rheumatism requiring further imaging to confirm the diagnosis

Exclusion Criteria5

Refusal or contra-indication to perform ultrasound or dual energy scanning.
Patient's opposition to the use of his or her health data for research purposes
Patient under guardianship or curatorship
Pregnant woman
Person not affiliated to a social security scheme or entitled to a social security benefit

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Interventions

OTHERData collection

The following data will be collected by the physician: sociodemographic profile, clinical manifestations, comorbidities, laboratory tests,etc. Diagnostic performance of different imagery techniques, performance of crystal deposit quantification in ultrasound and Dual-energy computed tomography (DECT), link between co-morbidities and volume of baseline crystal deposits then during monitoring, link between co-morbidities (including cardiovascular events and new diagnoses of co-morbidity) and vascular baseline crystal deposits and during follow-up, link between microcrystalline rheumatism activity and the quantity of crystal deposits in baseline imaging and during follow-up, link between co-morbidities and the evolution of microcrystalline baseline rheumatism and then during follow-up, link between co-morbidities and the evolution of crystal deposition volumes, the concordance of the evaluation of uratic stocks and their evolution between the imagery means.