RecruitingPhase 1Phase 2NCT04700527

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

LCCC2032: The Effects of Short Chain Fatty Acid Supplementation on the Quality of Life and Treatment-related Toxicities in Subjects Receiving Abdominopelvic Radiotherapy: A Randomized Controlled Study

Sponsor

UNC Lineberger Comprehensive Cancer Center

Enrollment

122 participants

Start Date

Dec 15, 2023

Study Type

INTERVENTIONAL

Conditions

Toxicity Radiation Toxicity

Summary

The purpose of this study is to assess and compare GI toxicity from RT between subjects who receive therapeutic SCFA and those who receive placebo, in hopes of identifying a safe, low-cost therapeutic to reduce GI toxicity from therapeutic or environmental radiation.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Short Chain Fatty Acid and a drug called Tapioca Flour for people with radiation toxicity and toxicity. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGShort Chain Fatty Acid

Participants will take the supplement as prescribed to determine if it can help with GI toxicity

DRUGTapioca Flour

Participants taking this will be used as a control group compared to those receiving the SCFA supplement

Locations(1)

Flora Danquah

Chapel Hill, North Carolina, United States

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NCT04700527

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