Radiation Toxicity Clinical Trials

21 recruiting

Radiation Toxicity Trials at a Glance

21 actively recruiting trials for radiation toxicity are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Utrecht, Caen, and Amsterdam. Lead sponsors running radiation toxicity studies include University of Aarhus, CNAO National Center of Oncological Hadrontherapy, and Bernardino Clavo, MD, PhD.

Browse radiation toxicity trials by phase

Treatments under study

About Radiation Toxicity Clinical Trials

Looking for clinical trials for Radiation Toxicity? There are currently 21 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Radiation Toxicity trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Radiation Toxicity clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 21 trials

Recruiting
Not Applicable

Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.

PainHead and Neck CancerQuality of Life+6 more
Mucosa Innovations, S.L.63 enrolled1 locationNCT05635929
Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Breast CancerLiver CancerEsophageal Cancer+35 more
UMC Utrecht8,000 enrolled18 locationsNCT04075305
Recruiting

Curatively Intended Thoracic Reirradiation

Radiotherapy Side EffectLung CancerThoracic Cancer+2 more
University of Aarhus500 enrolled1 locationNCT06950073
Recruiting
Not Applicable

Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy

Sexual DysfunctionRadiation ToxicityDyspareunia+1 more
Indiana University20 enrolled3 locationsNCT06059586
Recruiting
Phase 3

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Radiation ToxicityBrain MetastasasesHigh Grade Glioma (III or IV)+4 more
The Netherlands Cancer Institute408 enrolled5 locationsNCT06888817
Recruiting
Early Phase 1

A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer

Prostate CancerRadiation ToxicityUrinary Complication
University of Rochester30 enrolled1 locationNCT05530655
Recruiting
Phase 1Phase 2

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

ToxicityRadiation Toxicity
UNC Lineberger Comprehensive Cancer Center122 enrolled1 locationNCT04700527
Recruiting

Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2022 and 2025

Chemotherapeutic ToxicityRadiation Toxicity
Bernardino Clavo, MD, PhD105 enrolled1 locationNCT05417737
Recruiting

Longitudinal Registry Including Patients Treated With Heavy Particles

Rare DiseaseRadiotherapy Side EffectCancer+3 more
CNAO National Center of Oncological Hadrontherapy3,000 enrolled1 locationNCT05203250
Recruiting
Not Applicable

Neurocognitive Impact of Different Irradiation Modalities for Patients With Grade I-II Skull Base Meningioma:

Radiation ToxicityMeningioma
Centre Francois Baclesse108 enrolled3 locationsNCT06036706
Recruiting
Phase 2

The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor

Radiation ToxicityProton RadiotherapyThymus Epithelial Tumor
Jian Chen55 enrolled1 locationNCT06311968
Recruiting

Precision Radiotherapy for Tumours Using Magnetic Resonance-guided Linear Accelerator (MR-Linac)

Quality of LifeOncologyRadiation Toxicity+1 more
The Second Affiliated Hospital of Hainan Medical University3,000 enrolled1 locationNCT06531681
Recruiting
Not Applicable

Integrative Molecular Analysis of Individual Radiosensitivity in Pediatric Oncology

Radiation ToxicityPediatric CancerRadiosensitivity
Neolys100 enrolled2 locationsNCT06033183
Recruiting

Retrospective-perspective Observational Cohort Study on Toxicity and Efficacy of Radiotherapy in Pediatric and Adult Patients With Pediatric Histology Treated at the Pediatric Radiotherapy of the CRO in Aviano

Radiation Toxicity
Centro di Riferimento Oncologico - Aviano280 enrolled1 locationNCT06639165
Recruiting
Phase 2

Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis

Esophageal CancerRadiation ToxicityEsophagitis
First Affiliated Hospital of Chengdu Medical College120 enrolled1 locationNCT06392971
Recruiting
Not Applicable

Esophagus-sparing Radiotherapy for Metastatic Spinal Cord Compression.

Patient Reported Outcome MeasuresRadiation ToxicityEsophagitis+1 more
Herlev Hospital200 enrolled2 locationsNCT05109819
Recruiting
Not Applicable

A Novel Target Delineation Scheme in High-grade Glioma Patients: a Randomized Single-blind Clinical Trial

Radiation ToxicityHigh Grade GliomaMRI Simulated Positioning
Zhujiang Hospital88 enrolled1 locationNCT06215495
Recruiting

COr Loco-regional Advanced Lung Cancer Treated With Chemo-radiotherapy (COLA)

Radiation ToxicityCardiac ToxicityLung Cancer Stage II+2 more
Odense University Hospital100 enrolled1 locationNCT05258448
Recruiting

POst-Prostatectomy Ablative Radiation Therapy

Radiation Toxicity
University of Milano Bicocca30 enrolled2 locationsNCT04831970
Recruiting

Cognitive Function After Radiation Therapy for Primary Brain Tumours

Cognitive ImpairmentRadiation ToxicityPrimary Brain Tumour
University of Aarhus300 enrolled5 locationsNCT04306432