The Impact of Endometrial Compaction on Assisted Reproductive Technology Outcome
Zagazig University
356 participants
Jan 29, 2021
OBSERVATIONAL
Conditions
Summary
Absence of endometrial compaction on the day of ET has adverse effects on success of ART outcome.
Eligibility
Inclusion Criteria3
- All women should have the following:
- Aged from 18 - 37 years old. Undergoing fresh ICSI cycles. A normal uterus with no anomalies or pathologies. At least one good-quality embryo/blastocyst available for transfer (3 BB and more according to Gardner and Schoolcraft grading system).
- Easy mockup embryo transfer (i.e. the catheter is smoothly inserted without touching the fundus, no cervix tenaculum is used and the catheter is clean of blood).
Exclusion Criteria1
- \- Younger than 18 or older than 37 years old. Congenital uterine abnormality or pathology. Presence of a hydrosalpinx. Chronic diseases which are not suitable for pregnancy. ICSI cycles with fresh or frozen TESE samples.
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Interventions
Blood sampling: Serum P4 \& estradiol will be performed on the day of triggering and on the day of embryo transfer. Progesterone/ Estradiol (P4/E2) ratio will be calculated Ultrasound: On triggering day, at time of ovum pick up and on ET day, we will measure 1. Endometrial thickness 2. Endometrial pattern 3. Endometrial compaction: the difference in measurement of endometrial thickness between the day of embryo transfer and the day of triggering. 4. Junctional zone thickness 5. Uterine contraction (peristalsis). 6. Blood flow of uterine vessels: PI of the uterine arteries will be calculated also Endometrial - sub endometrial blood flow
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04721522