RecruitingNot ApplicableNCT04754087

G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study

Global, Multicenter, and Prospective Post-Market Clinical Follow-Up Study of the G7 Acetabular System With Vivacit-E and Longevity Highly Crosslinked Polyethylene (HXLPE) Liners & Instrumentation


Sponsor

Zimmer Biomet

Enrollment

300 participants

Start Date

Jul 7, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The main objectives of this study are to confirm the long-term safety, performance, and clinical benefits of the G7 Acetabular Shells when used with the Vivacit-E and Longevity HXLPE liners and instrumentation in primary and revision total hip arthroplasty.


Eligibility

Min Age: 18 Years

Inclusion Criteria9

  • Patient must be a legal adult who has reached full skeletal maturity.
  • Patient must be treated for one of the following indications:
  • Noninflammatory degenerative joint disease including osteoarthritis and avascular necrosis
  • Rheumatoid arthritis
  • Correction of functional deformity
  • Treatment of non-union, femoral neck fracture, and trochanteric fractures of the proximal femur with head involvement, unmanageable by other techniques
  • Revision procedures where other treatment or devices have failed
  • Patient must be able and willing to complete the protocol required follow-up visits.
  • Patient must be able and willing to sign the Institutional Review Board or Ethics Committee (IRB/EC) approved informed consent.

Exclusion Criteria10

  • Patient presents with osteoporosis, which in the opinion of the Principal Investigator, may limit the subject's ability to support total hip arthroplasty using the study device.
  • Patient has a metabolic disorder that may impair bone formation.
  • Patient has osteomalacia.
  • Patient has distant foci of infections which may spread to the implant site or patient with infection, sepsis or osteomyelitis.
  • Patient has rapid joint destruction, marked bone loss or bone resorption apparent on roentgenogram.
  • Patient has a vascular insufficiency, muscular atrophy, or neuromuscular disease
  • Patient is a prisoner.
  • Patient is a current alcohol or drug abuser.
  • Uncooperative patient or patient with neurologic disorders who is incapable or unwilling to follow directions.
  • Patient is pregnant.

Interventions

DEVICEVivacit-E and Longevity (HXLPE) Liners

This is a dual cohort study in which 150 subjects will receive the Vivacit-E (HXLPE) Liner and 150 subjects will receive the Longevity (HXLPE) Liner.


Locations(11)

Colorado Joint Replacement

Denver, Colorado, United States

South Bend Orthopaedics

South Bend, Indiana, United States

Duke University Medical Center

Durham, North Carolina, United States

Slocum Center for Orthopedics & Sports Medicine

Eugene, Oregon, United States

Oregon Health and Science University

Portland, Oregon, United States

University of Utah Health

Salt Lake City, Utah, United States

Copenhagen University Hospital Hvidovre

Hvidovre, Denmark

Zuyderland Hospital

Geleen, Netherlands

OCON Hengelo

Hengelo, Netherlands

Skane University Hospital

Lund, Sweden

The Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust Royal Bournemouth Hospital

Bournemouth, UK, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT04754087


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