RecruitingNot ApplicableNCT04797364

Pharmacogenetic Supported Prescribing in Kids

Sponsor

University of Calgary

Enrollment

6,000 participants

Start Date

Jan 18, 2021

Study Type

INTERVENTIONAL

Conditions

Mental Health Impairment

Summary

Implementation of pharmacogenetic testing for children and adolescents aged 6-24 who are starting or changing psychiatric medication.

Eligibility

Min Age: 6 YearsMax Age: 24 Years

Plain Language Summary

Simplified for easier understanding

This trial explores whether genetic testing can help doctors choose better psychiatric medications for children and teens by understanding how each child's body processes drugs. **You may be eligible if...** - Your child's medical records are available - Your child's doctor recommends starting, changing, or adjusting a psychiatric medication - The treating doctor is licensed in Alberta, British Columbia, Saskatchewan, or Manitoba **You may NOT be eligible if...** - Your child is medically unstable or cannot give informed consent - Your child is unwilling to provide a saliva sample for genetic testing - Your child has a history of liver or bone marrow transplant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTPharmacogenetic Testing

Participants will donate a 2ml (teaspoon) sample of saliva. DNA extracted from the saliva sample will be used for genotyping. Genotyping results will be translated into an interpretative clinical report using evidence-based software (Sequence2Script) developed by our group and delivered to the treating physician for use in their clinical decision-making. The report will contain genotyping results, predicted phenotype, and evidence-based drug selection and dosing recommendations relevant to the child's current and future care