RecruitingNot ApplicableNCT04798651

Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis


Sponsor

University Hospital, Bordeaux

Enrollment

150 participants

Start Date

Sep 30, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The study aims at identifying the type of B and CD4 T cell subsets with pathogenic properties in the different clinical forms of multiple sclerosis. This research might open new therapeutic approaches for the treatment of multiple sclerosis particularly progressive MS.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is researching how certain immune cells in the blood and spinal fluid contribute to multiple sclerosis (MS), a disease where the immune system mistakenly attacks the brain and spinal cord. Researchers want to better understand why the disease progresses and find new ways to treat it. **You may be eligible if...** - You are 18 or older - You have been diagnosed with multiple sclerosis (using the 2010 McDonald criteria) or have had a first episode that may be MS - You are already scheduled for a blood draw or spinal fluid test for diagnosis or treatment purposes - You have health insurance coverage - You are willing to participate **You may NOT be eligible if...** - You are pregnant or breastfeeding - You are a minor, deprived of liberty by court order, or legally unable to give consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BIOLOGICALblood sample

28 ml whole blood for Peripheral blood mononuclear cell (PBMC) and monocytes isolation

BIOLOGICALcerebro-spinal fluid

1 ml of cerebro-spinal fluid


Locations(1)

CHU de Bordeaux - service de neurologie

Bordeaux, France

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT04798651


Related Trials