RecruitingNot ApplicableNCT04802603

Dose-Escalated Spine SbRT for Localized Metastasis to the Spinal Column

Dose-Escalated Spine SbRT (DESSRT) for Localized Metastasis to the Spinal Column

Sponsor

Baptist Health South Florida

Enrollment

60 participants

Start Date

Mar 14, 2021

Study Type

INTERVENTIONAL

Conditions

Spine Metastases Metastasis Spine

Summary

This study is being done to determine the feasibility and tolerability of a novel regimen of spine stereotactic radiosurgery (SSRS). SSRS delivers high doses of radiation to tumors of the spine using precision techniques. In standard medical care, conventional SSRS is delivered in only 1 or 2 treatments. When this treatment is delivered in only 1-2 treatments, a high dose is used which can increase the side effects of treatment. This study aims to test an alternative technique of delivering SSRS over 5 treatments. By delivering the radiation therapy over multiple treatments, the dose of radiation is less per treatment.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Spine stereotactic body radiotherapy for people with metastasis spine and spine metastases. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONSpine stereotactic body radiotherapy

Cohort 1 - De novo: Spine stereotactic body radiotherapy to a dose of 40 Gy in 5 fractions. Cohort 2 - Prior radiotherapy: Risk-adapted spinal cord tolerance based on prior spine stereotactic body radiotherapy to a dose of 40 Gy in 5 fractions.