MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer

This study is testing an advanced form of radiation therapy — guided by MRI imaging in real time — for rectal cancer to see whether precise, adaptive treatment can shrink the tumor enough to avoid surgery altogether, preserving the rectum and quality of life. **You may be eligible if...** - You are 18 or older - You have rectal cancer confirmed by biopsy (adenocarcinoma) - Your cancer is Stage I, II, or III (has not spread to distant organs, or has only equivocal/uncertain distant findings) - You are a candidate for curative treatment **You may NOT be eligible if...** - You have confirmed distant metastases - You have inflammatory bowel disease - You have had prior pelvic radiation - You have a pacemaker or other MRI-incompatible implant Talk to your doctor to see if this trial is right for you.