RecruitingNot ApplicableNCT04820127

Personalized Management of Psycho-behavioral Symptoms in Alzheimer's Disease: Impact on Health Resources Use

Personalized Management of Psycho-behavioral Symptoms in Alzheimer's Disease and Related Disorders: Impact on Health Resources Use


Sponsor

University Hospital, Toulouse

Enrollment

668 participants

Start Date

Oct 14, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The present project propose to study the effectiveness of a personalized care management of psycho-behavioral symptoms based on an evidence-based standardized assessment to identify and understand the underlying causes of psycho-behavioral symptoms followed by a personalized intervention based on targeted and prioritized actions. This personalized intervention is proposed both to Alzheimer disease (AD) patients living at home with agitation-type psycho-behavioral symptoms, and also to their caregivers with the support and coordination of a nurse working in collaboration with the specialist physician and the General Practitioner (GP). News technologies are used to enhance the follow-up, based on telehealth, and caregiver training. The project hypothesize that, for a vulnerable population at risk (AD patient with agitation and their caregivers) living at home, a personalized intervention, carried out and coordinated by a nurse in close collaboration with the specialist and GP, would reduce hospitalizations and have a positive effect on the disease evolution and caregiver distress. Also this personalized intervention could reduce the cost of care, in particular by reducing the costs associated with hospitalizations and informal help.


Eligibility

Min Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a personalized approach to managing behavioral and psychological symptoms in people with Alzheimer's disease and other forms of dementia — such as agitation, restlessness, and distress. Researchers want to see if tailoring care to each individual person reduces the need for hospitalizations and other costly medical resources. **You may be eligible if...** - You have been diagnosed with a major neurocognitive disorder (such as Alzheimer's disease) at any stage - You live at home (not in a care facility) - You have a family member or close person who helps care for you at least 6 hours per week - You have been experiencing agitation for at least one month - Your agitation is at least mild in severity **You may NOT be eligible if...** - You live in a care home or residential facility - You do not have a regular caregiver available to attend study visits - You do not have agitation as a symptom Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALpersonalized care preceded by a standardized assessment

* personalized intervention plan (PIP) proposed to the patient/caregiver dyad to correct potentially reversible causes of psycho-behavioral symptoms. This PIP will be re-evaluated and adapted at each visit by the nurse in close collaboration with the GP; * PIP implementation will be based on a close follow-up during the 18 months follow-up coordinated by the nurse (3 memory consultation visits, 3 home visits (with the GP) and 6 phone calls). This follow up will be enhanced with the use of a web platform (allowing teleconsultation, tele-expertise and telemonitoring); * specific training on psycho-behavioral symptoms for caregivers at baseline and during follow-up will be performed. On line training on psycho-behavioral symptoms management for GP will be available;


Locations(16)

CH d'Albi

Albi, France

CH de Cahors

Cahors, France

Carcassonne Hospital

Carcassonne, France

CHI Castres Mazamet

Castres, France

CH Lannemezan

Lannemezan, France

CH Lavaur

Lavaur, France

Limoges university hospital

Limoges, France

Lyon University Hospital

Lyon, France

CH Montauban

Montauban, France

Narbonne Hospital

Narbonne, France

Perpignan Hospital

Perpignan, France

CHI Val d'Ariège

Saint-Girons, France

Toulouse University Hospital (CHU de Toulouse)

Toulouse, France

University Hospital Toulouse - Neurology department

Toulouse, France

CH de Bigorre

Vic-en-Bigorre, France

HNO-Franche-sur-Soâne

Villefranche-sur-Saône, France

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NCT04820127


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