RecruitingPhase 4NCT04849455

Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection

Erector Spinae Plane Block Catheters: The Role in Acute Postoperative Pain After Hepatic Resection With Intrathecal Morphine


Sponsor

University of California, San Diego

Enrollment

70 participants

Start Date

May 24, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

To determine whether the addition of erector spinae plane (ESP) catheters to existing multimodal analgesic regimen with intrathecal morphine provides superior postoperative analgesia in patients undergoing hepatic resection compared with patients not receiving ESP catheters.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • undergoing hepatic resection
  • Admitting service requests APS consult
  • >18 years old and able to provide consent

Exclusion Criteria7

  • pregnancy
  • incarceration
  • inability to communicate with the investigators and hospital staff
  • severe hepatic disease
  • chronic high-dose opioid use (defined as daily use for more than 4 weeks prior to surgery of at least the equivalent of 20 mg oxycodone);
  • BMI > 40 kg/m2
  • allergy to study medications (lidocaine, ropivacaine)

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Interventions

DRUG0.2% ropivacaine local anesthetic continuous erector spinae plane block

Treatment- continuous erector spinae block catheter followed by an infusion of ropivacaine 0.2% at 10ml automatic set bolus per 60 minute with 2ml/hr continuous infusion (12mls/hr total per catheter)

DRUG0.2% ropivacaine local anesthetic superficially taped continuous erector spinae plane block

Placebo- Superficially placed (taped to the surface) erector spinae block catheter with a ropivacaine 0.2% infusion at 0.1ml /hr

DRUGSpinal Morphine

200-300 mcg of spinal morphine


Locations(1)

University of California, San Diego

San Diego, California, United States

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NCT04849455


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