Periodontal Assessment of a Bariatric Care Population
Periodontal Assessment of a Bariatric Care Population, Clinical, Genetic and Microbiological Characteristics. A Cross-sectional Study.
Queen Mary University of London
394 participants
Jan 31, 2014
OBSERVATIONAL
Conditions
Summary
Our primary aim is to investigate the prevalence and severity of Periodonotal Disease (PD) in a population of obese patients. Our secondary objectives are to: Investigate inflammatory biomarkers that have been associated with PD in the saliva of obese patients. Investigate the association of FTO gene (Obesity) polymorphisms with the prevalence of PD in this population. Investigate and describe the subgingival microbial flora in obese patients with PD from subgingival dental plaque samples as well as the salivary samples.
Eligibility
Inclusion Criteria3
- Subject must be over 18 years of age.
- Subject must have a BMI of higher or equal to 30 kg/ m2
- Subject must have voluntarily given written informed consent.
Exclusion Criteria8
- Subject is currently involved in other research involving the use of antibiotics or novel or unknown medications.
- Self-reported pregnancy.
- Subject is on chronic treatment (i.e., two weeks or more) with specific medications known to affect periodontal status (phenytoin or cyclosporine) within one month of baseline visit.
- Subject knowingly has HIV or Viral Hepatitis.
- Patients are completely edentulous.
- Subject with uncontrolled systemic illnesses.
- Subject is not capable to give informed consent.
- Subjects on chronic antibiotic therapy (ie two weeks or more in the previous month).
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Locations(4)
View Full Details on ClinicalTrials.gov
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NCT04851470