RecruitingNCT04852354

Tissue Collection for Drug Screening and Bioanalysis

Sponsor

Weill Medical College of Cornell University

Enrollment

500 participants

Start Date

Jul 22, 2020

Study Type

OBSERVATIONAL

Conditions

Central Nervous System Tumor

Summary

The purpose of this study is to improve upon the knowledge currently available about central nervous system (CNS) tumors. We will study the different characteristics of these tumors using tissue samples collected during surgery and post-autopsy. The aim is to create tumor cell lines and models to test how they respond to different drugs. This research will help improve treatment options and identify new targets for therapy.

Eligibility

Inclusion Criteria15

Subject has presented with a suspected/confirmed neoplastic CNS lesion and is undergoing a neurosurgical procedure in which CNS tissue and/or tumors associated with this tissue will be removed.
There must be tissue available in excess of that required by neuropathology for diagnostic purposes.
Subject of all ages included.
Subjects who are pregnant can be included.
Subjects who are neonates (0-4 weeks) can be included.
Subject is between 4 weeks and 21 years of age and is undergoing a neurosurgical procedure at WCMC.
Subject does not have a CNS tumor diagnosis.
Subject should not be pregnant at the time of enrollment.
Subject of all ages included
Subject has been diagnosed with a neoplastic CNS lesion at the time of passing.
Subjects who are pregnant can be included.
Subjects who are neonates (0-4 weeks) can be included.
Subject is the biological parent of a patient undergoing/ who underwent a neurosurgical procedure in which CNS tissue and/or tumors associated with this tissue will be/ was removed.
Subject is the biological parent of patient enrolled in cohort 1.
Subject is not pregnant at the time of enrollment.