Central Nervous System Tumor Clinical Trials

8 recruiting

Central Nervous System Tumor Trials at a Glance

15 actively recruiting trials for central nervous system tumor are listed on ClinicalTrialsFinder across 6 cities in 4 countries. The largest study group is Phase 1 with 7 trials, with the heaviest enrollment activity in New York, Ann Arbor, and Atlanta. Lead sponsors running central nervous system tumor studies include Memorial Sloan Kettering Cancer Center, Beijing Tiantan Hospital, and Beijing InnoCare Pharma Tech Co., Ltd..

Browse central nervous system tumor trials by phase

Treatments under study

About Central Nervous System Tumor Clinical Trials

Looking for clinical trials for Central Nervous System Tumor? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Central Nervous System Tumor trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Central Nervous System Tumor clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting

Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients

Solid, Liquid, Central Nervous System Tumors
St. Jude Children's Research Hospital2,500 enrolled1 locationNCT02530658
Recruiting
Phase 1Phase 2

A Study of Mirdametinib in People With Central Nervous System Tumors

GliomaCentral Nervous System Tumors
Memorial Sloan Kettering Cancer Center26 enrolled7 locationsNCT07539441
Recruiting
Phase 1

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Germ Cell TumorChoroid Plexus CarcinomaCentral Nervous System Tumor+8 more
Seattle Children's Hospital90 enrolled1 locationNCT04185038
Recruiting
Phase 1

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

Central Nervous System TumorGlioblastomaCNS Tumor+5 more
Sabine Mueller, MD, PhD208 enrolled6 locationsNCT04732065
Recruiting
Phase 1

A Study of Avutometinib for People With Solid Tumor Cancers

Solid TumorSolid Tumor, AdultNeuroblastoma+12 more
Memorial Sloan Kettering Cancer Center23 enrolled2 locationsNCT06104488
Recruiting
Not Applicable

A Clinical Prediction Model for Surgical Site Infection After Central Nervous System Tumor Surgery

Central Nervous System TumorSurgical Site Infection (SSI)
Ming Yang500 enrolled1 locationNCT07378683
Recruiting

Integrated Cancer Repository for Cancer Research

Breast CancerLiver CancerEsophageal Cancer+47 more
University of Nebraska999,999 enrolled45 locationsNCT02012699
Recruiting

Somatic Mosaicism in Twins Discordant for Childhood Cancer

Central Nervous System TumorSomatic MutationPediatric Central Nervous System Tumor+1 more
Children's Oncology Group50 enrolled1 locationNCT06054295
Recruiting

Tissue Collection for Drug Screening and Bioanalysis

Central Nervous System Tumor
Weill Medical College of Cornell University500 enrolled1 locationNCT04852354
Recruiting
Phase 1

Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors

Pediatric Recurrent Central Nervous System Tumors
Washington University School of Medicine7 enrolled1 locationNCT03988283
Recruiting
Phase 1Phase 2

Study of ICP-723 in Patients With Advanced Solid Tumors or Primary Central Nervous System Tumors

Advanced Solid Tumors Harboring NTRK FusionPrimary Central Nervous System Tumors Harboring NTRK Fusion
Beijing InnoCare Pharma Tech Co., Ltd.70 enrolled1 locationNCT05745623
Recruiting

Brain Slice Explants to Predict Drug Response in Brain Tumors

Central Nervous System Tumor
UNC Lineberger Comprehensive Cancer Center50 enrolled1 locationNCT05978557
Recruiting
Phase 1Phase 2

OH2 Oncolytic Viral Therapy in Central Nervous System Tumors

Central Nervous System Tumors
Binhui Biopharmaceutical Co., Ltd.28 enrolled1 locationNCT05235074
Recruiting

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

LymphomaUnspecified Adult Solid Tumor, Protocol SpecificLeukemia+6 more
Barbara Ann Karmanos Cancer Institute1 locationNCT00935090
Recruiting

Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China

Germ Cell TumorGliomaBrain Tumor, Pediatric+3 more
Beijing Tiantan Hospital400 enrolled1 locationNCT05672043