RecruitingNot ApplicableNCT04855630

Combating Alzheimer's Through Sleep and Exercise

Combating Alzheimer's Through Sleep and Exercise (CASE)


Sponsor

University of Miami

Enrollment

30 participants

Start Date

Mar 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research is to see how sleep and exercise affects dementia risk over time.


Eligibility

Min Age: 45 YearsMax Age: 80 Years

Inclusion Criteria8

  • Able to perform mild exercise
  • Able to wear DREEM 2 Headband
  • Able to wear a Fitbit wrist watch
  • Able to perform the Everlywell biomarker procedure
  • Able to Understand and Speak English
  • Able to operate a digital device like mobile phone, iPad, or computer
  • Self-reported history of problems with cognitive impairment: memory, concentration, and processing information
  • Only participants cognitively able and willing to provide consent will be included.

Exclusion Criteria5

  • Prohibited from or unable to perform mild exercise
  • Unable to wear wrist watch or headband devices, or unable to supply pinprick blood sample for any reason
  • Unable to speak or understand English
  • Unable to use mobile device/smartphone technology
  • Unable or unwilling to consent for any reason.

Interventions

DEVICEDREEM 2 Headband

Participants will wear the DREEM 2 headband for 3 months for a minimum of 4 out of 7 nights per week and will participate in its digital therapeutic Cognitive Behavioral Therapy - Insomnia (CBT-I) intervention (entails brain stimulation to improve slow wave sleep and sleep hygiene counseling tips to improve sleep behaviors).

OTHERExercise Routine

Participants will partake in a guided exercise routine. Each routine consists of 30-minute mild circuit training session twice per week for 3 months.


Locations(1)

University of Miami Hospitals

Miami, Florida, United States

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NCT04855630


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