Dementia Clinical Trials

379 recruiting

Dementia Trials at a Glance

422 actively recruiting trials for dementia are listed on ClinicalTrialsFinder across 6 cities in 47 countries. The largest study group is Not Applicable with 170 trials, with the heaviest enrollment activity in Boston, Toronto, and New York. Lead sponsors running dementia studies include The University of Hong Kong, Emory University, and Duke University.

Treatments under study

About Dementia Clinical Trials

Looking for clinical trials for Dementia? There are currently 379 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Dementia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Dementia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 422 trials

Recruiting

Genetic Characterization of Movement Disorders and Dementias

DementiaMovement Disorder
National Institute on Aging (NIA)12,000 enrolled1 locationNCT02014246
Recruiting
Not Applicable

Transcranial Pulse Stimulation of the Brain

Mild DementiaAging Well
University of Florida20 enrolled1 locationNCT05910619
Recruiting
Not Applicable

Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia

Dementia of Alzheimer TypeHearing Loss, SensorineuralAmnestic Mild Cognitive Impairment
Northwestern University20 enrolled2 locationsNCT04240561
Recruiting
Not Applicable

The REMINDER4Care Program for Older Adults Supported by Residential and Daycare Facilities

PreventionDementia Risk Factors
University of Coimbra100 enrolled1 locationNCT06922071
Recruiting
Not Applicable

Aerobic Exercise for Older Adults at Increased Risk of Alzheimer's Disease and Related Dementias

DementiaAlzheimer Disease
University of Calgary264 enrolled1 locationNCT03035851
Recruiting
Not Applicable

Electroconvulsive Therapy (ECT) for Agitation in Dementia (AD)

Alzheimer DementiaAgitation,Psychomotor
Brent Forester50 enrolled5 locationsNCT03926520
Recruiting
Not Applicable

NiteCAPP: Web-based Interventions for Insomnia in Rural Dementia Caregivers

InsomniaDementia
University of South Florida100 enrolled1 locationNCT04896775
Recruiting

Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Amyotrophic Lateral SclerosisFrontotemporal DementiaProgressive Supranuclear Palsy
National Institute of Neurological Disorders and Stroke (NINDS)360 enrolled1 locationNCT03225144
Recruiting
Not Applicable

Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients

ALS (Amyotrophic Lateral Sclerosis)ALSFTDFrontal Temporal Dementia (FTD)
Centre hospitalier de l'Université de Montréal (CHUM)150 enrolled1 locationNCT06051123
Recruiting

Genetic Studies of Early-onset Dementia

Mild Cognitive Impairment (MCI)Alzheimer Dementia (AD)Memory Loss+1 more
Columbia University1,000 enrolled1 locationNCT04906863
Recruiting
Phase 1

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

DementiaParkinson's Disease
National Institute of Mental Health (NIMH)184 enrolled1 locationNCT04396873
Recruiting

Investigating Dynamic Interactions in Distributed Cognitive Control Networks

Cognitive ImpairmentDementiaDepression+1 more
University of Alabama at Birmingham30 enrolled1 locationNCT05927974
Recruiting
Not Applicable

Retinal Hyperspectral Imaging in Neurodegenerative Diseases

DementiaAlzheimer DiseaseParkinson Disease+5 more
Center for Eye Research Australia930 enrolled1 locationNCT07545473
Recruiting
Not Applicable

A Multifocal tDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia

DementiaAlzheimer DiseaseAlzheimer Disease, Early Onset+1 more
University of Campania Luigi Vanvitelli50 enrolled1 locationNCT06668610
Recruiting

Large Language Model for Understanding and Monitoring Elderly Neurocognition

Dementia
Northumbria Healthcare NHS Foundation Trust60 enrolled1 locationNCT07347431
Recruiting
Phase 2

Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis

Lewy Body Dementia Psychosis
ACADIA Pharmaceuticals Inc.180 enrolled54 locationsNCT07029581
Recruiting
Not Applicable

Virtual Reality for Caregiver Assembly, Relief, Empowerment, and Support (VR-CARES)

Dementia CaregiverDirect Care WorkersIn-Home Care
Rendever, Inc.30 enrolled6 locationsNCT07430371
Recruiting
Not Applicable

The Black Immigrant Project

Dementia
University of Minnesota150 enrolled1 locationNCT07546708
Recruiting
Not Applicable

Intervention for Communication Quality of Life in Primary Progressive Aphasia

Primary Progressive Aphasia(PPA)Progressive AphasiaLogopenic Progressive Aphasia (LPA)+9 more
Maya Henry30 enrolled1 locationNCT07219680
Recruiting
Not Applicable

BrainLive Connect: Non-professional Delivered CST for People Living With Dementia

Dementia
The University of Hong Kong520 enrolled1 locationNCT07531589