Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer

This study tests whether eating white button mushrooms daily can reduce inflammation in overweight postmenopausal women who are at high risk of developing breast cancer. Mushrooms contain compounds thought to have anti-inflammatory and hormone-modulating properties. **You may be eligible if...** - You are a postmenopausal woman with a BMI of 30 or higher (obese) - You are at high risk of breast cancer based on genetic mutations (BRCA1/2), family history, prior breast biopsy results, a Gail Risk score of 1.7 or higher, or a prior T1/T2 breast cancer diagnosis more than 5 years ago **You may NOT be eligible if...** - You have active or recently diagnosed breast cancer - You are premenopausal - You are not considered high risk for breast cancer - You have health conditions that would prevent participation or affect the study results Talk to your doctor to see if this trial is right for you.