RecruitingNot ApplicableNCT04921917

Exercise and Soft Tissue Sarcoma

The Effect of Exercise on Patient Outcomes During Treatment of Soft Tissue Sarcoma With Neoadjuvant Radiation Therapy and Surgical Resection


Sponsor

Duke University

Enrollment

24 participants

Start Date

Apr 30, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the effect of a neoadjuvant (i.e. pre-treatment) exercise regimen on extremity function and postoperative wound healing. The study group will include patients with a primary diagnosis of soft tissue sarcoma undergoing treatment with neoadjuvant radiation therapy and surgical resection. Patients with upper or lower extremity sarcomas will be considered for enrollment.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether an exercise program before and after surgery improves healing and recovery in people with soft tissue sarcoma (a type of cancer in muscle or connective tissue) of the arm or leg who are receiving radiation followed by surgery. **You may be eligible if:** - You are 18–85 years old, male or female - You have a confirmed diagnosis of soft tissue sarcoma in an arm or leg - Your treatment plan includes neoadjuvant (pre-surgery) radiation followed by surgical removal - Your surgeon expects to close the wound primarily at the time of surgery **You may NOT be eligible if:** - Your cancer is not in an arm or leg - Your treatment plan does not include radiation before surgery - You have had prior radiation to the same area - You are currently on high-dose steroids or active chemotherapy - You are not able to give your own informed consent - You are planning to receive radiation after surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERneoadjuvant exercise therapy

brief exercise regimen completed immediately prior to neoadjuvant radiation therapy. Rubber bands will be used for the exercise training of patients with lower extremity tumors while an electronic hand-held dynamometer will be used for the exercise training for patients with upper extremity tumors.


Locations(1)

Duke University

Durham, North Carolina, United States

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NCT04921917


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