RecruitingPhase 4NCT04921943

Hypertonic Saline for MAC

Hypertonic Saline for Treatment of Pulmonary Mycobacterium Avium Complex (MAC) Disease


Sponsor

Oregon Health and Science University

Enrollment

50 participants

Start Date

May 18, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The MAC-HS study is a testing whether hypertonic saline helps improve symptoms and clearance of mycobacteria in patients with M. avium complex lung infections.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Azithromycin, a drug called Ethambutol, and others for people with nontuberculous mycobacterial lung disease and nontuberculous mycobacterium infection. The study is currently recruiting participants at 3 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGHypertonic saline

Nebulizing with 7% hypertonic saline twice daily for 12 weeks.

DRUGAzithromycin

Standard of care

DRUGEthambutol

Standard of care

DRUGRifampin

Standard of care


Locations(3)

NYU Langone Health

New York, New York, United States

Oregon Health & Science University

Portland, Oregon, United States

University Health Network

Toronto, Ontario, Canada

View Full Details on ClinicalTrials.gov

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NCT04921943


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