RecruitingNCT04939571

European Disease Registry on Retinopathy of Prematurity (ROP)


Sponsor

University Medicine Greifswald

Enrollment

3,000 participants

Start Date

Aug 6, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The EU-ROP registry is a European wide multicenter non-interventional observational registry study intended to run open-ended in as many countries as possible including infants treated for retinopathy of prematurity irrespective of the used treatment modality. The registry is strictly observational; only clinical routine data is collected, no study-specific examinations or interventions are to be performed. The aim of the EU-ROP registry is to collect information on as many patients as possible treated for ROP in Europe. Both the number of study centers as well as the number of patients to be included into the registry are not limited. The primary objective is to describe the typical clinical features of infants with severe ROP, variations in phenotype, and the clinical progression of the disease over time (natural history) in different European countries as well as to study treatment patterns, follow-up patterns, as well as long-term outcomes.


Eligibility

Inclusion Criteria1

  • ROP requiring treatment according to the respective national ROP screening and treatment guidelines

Exclusion Criteria1

  • Denial or absence of consent for documentation and electronic storage of personal data by parents or legal guardians

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Interventions

OTHERRegistry of preterm born infants with treatment-requiring ROP

All prematurely born infants who develop treatment requiring ROP and are treated (independent of the kind of treatment modality) at a center that participates in the registry are eligible for database entry.


Locations(59)

University Eye Hospital Salzburg

Salzburg, Austria

University Hospital Saint George

Plovdiv, Bulgaria

Acibadem City Clinic Tokuda Hospital

Sofia, Bulgaria

University Eye Hospital Alexandrovska

Sofia, Bulgaria

University Eye Hospital Tartu

Tartu, Estonia

Hospital Rothschild

Paris, France

University Eye Hospital

Aachen, Germany

University Eye Hospital Helios

Berlin, Germany

University Eye Hospital Vivantes

Berlin, Germany

University Eye Hospital Bonn

Bonn, Germany

Braunschweig Muncipal Hospital

Braunschweig, Germany

University Eye Hospital

Chemnitz, Germany

University Eye Hospital

Cologne, Germany

Carl-Thiem University Hospital Cottbus

Cottbus, Germany

University Eye Hospital

Düsseldorf, Germany

University Eye Hospital

Freiburg im Breisgau, Germany

University Eye Hospital Fulda

Fulda, Germany

University Eye Hospital Gießen

Giessen, Germany

University Eye Hospital

Göttingen, Germany

University Eye Hospital

Greifswald, Germany

University Eye Hospital

Hamburg, Germany

University Eye Hospital Hannover

Hanover, Germany

Facharztpraxis für Augenheilkunde

Ludwigshafen, Germany

University Eye Hospital

Lübeck, Germany

Ludwig-Maximilins-University Munich

Munich, Germany

Augenzentrum am St. Franziskus-Hospital

Münster, Germany

University Eye Hospital

Münster, Germany

Nuremberg South Hospital

Nuremberg, Germany

Ernst-von-Bergmann Hospital

Potsdam, Germany

University Eye Hospital

Regensburg, Germany

University Eye Hospital

Tübingen, Germany

University Eye Hospital Ulm

Ulm, Germany

P&A Kyriakou Athens Children Hospital

Athens, Greece

Department of Ophthalmology University Hospital of Larissa

Larissa, Greece

Aristotle University of Thessaloniki

Thessaloniki, Greece

University Clinical Center of Kosovo

Pristina, Kosovo

Medical University of Bialystok Children's Clinical Hospital

Bialystok, Poland

University Hospital in Bydgoszcz

Bydgoszcz, Poland

University Hospital in Zabrze Silesia

Katowice, Poland

Prof. Dr. Stanislaw Popowski Regional Specialized Children's Hospital

Olsztyn, Poland

University of Medical Sciences Poznan

Poznan, Poland

Children's Memorial Health Institute Warsaw

Warsaw, Poland

Biomédica de Málaga y Plataforma en Nanomedicina

Málaga, Spain

University and Polytechnic Hospital La Fe

Valencia, Spain

University Eye Hospital Genève

Geneva, Switzerland

University Eye Hospital Cukurova

Adana, Turkey (Türkiye)

Etlik Zübeyde Hanim Women's Health Education and Research Hospital

Ankara, Turkey (Türkiye)

Hacettepe University Children's Hospital

Ankara, Turkey (Türkiye)

University Eye Hospital Ankara

Ankara, Turkey (Türkiye)

University Eye Hospital Baskent

Ankara, Turkey (Türkiye)

University Eye Hospital Gazi

Ankara, Turkey (Türkiye)

University Eye Hospital Uludag

Bursa, Turkey (Türkiye)

Umraniye Research and Education Hospital

Istanbul, Turkey (Türkiye)

University Eye Hospital Koc

Istanbul, Turkey (Türkiye)

Ordu University Medical Faculty

Ordu, Turkey (Türkiye)

Ondokuz Mayis University Eye Hospital

Samsun, Turkey (Türkiye)

Department of Pediatric Ophthalmology and Eye Microsurgery Perinatal Center Kiev

Kiev, Ukraine

Kyiv Pediatric Hospital Ohmatdyt

Kiev, Ukraine

Filatov Institute of Eye Diseases and Tissue Therapy Odessa

Odesa, Ukraine

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