RecruitingNCT04945603

Poor Grade Aneurysmal Subarachnoid Hemorrhage Study Group

Poor Grade Aneurysmal Subarachnoid Hemorrhage Multicentric Study Group


Sponsor

IRCCS San Raffaele

Enrollment

800 participants

Start Date

May 25, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Multicentric registry study in order to define outcome, predictors, treatment effects and their modifiers in poor grade aneurysmal subarachnoid haemorrhage patients. The search for outcome predictors is going to be subdivided into three main research areas: 1. outcome predictors in the emergency department (so called "early brain injury phase"). 2. outcome predictors in the neurocritical care unit (so called "delayed brain injury phase"). 3. Treatment strategies. Two other areas of research are identified: delayed cerebral ischemia (incidence, treatment, predictors, impact on outcome) and long term follow-up (recent evidences suggest that there may be a non-negligible proportion of poor grade subarachnoid hemorrhage patients who may benefit from substantial improvement at long-term (after 6-12 months of follow-up).


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Patients admitted to the emergency department because of aneurysmal subarachnoid hemorrhage of poor grade (IV-V) according to the WFNS classification.

Exclusion Criteria3

  • Patients younger than 18 years old.
  • Pregnant or breast-feeding patients.
  • Aneurysmal subarachnoid hemorrhage due to trauma or vascular malformations other than cerebral aneurysms.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERStandard management according to international/national guidelines

Standard management according to international/national guidelines. Observational study


Locations(10)

ASST Ospedale Papa Giovanni XXIII

Bergamo, Italy

IRCCS Bellaria

Bologna, Italy

Azienda Ospedaliera Spedali Civili

Brescia, Italy

Ospedale Vito Fazzi

Lecce, Italy

IRCCS San Raffaele

Milan, Italy

Ospedale Maggiore della Città di Novara

Novara, Italy

Azienda Ospedaliero-Universitaria di Parma

Parma, Italy

Policlinico Universitario Agostino Gemelli

Roma, Italy

Ospedale Santissima Annunziata

Taranto, Italy

Azienda Ospedaliera Universitaria Integrata

Verona, Italy

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT04945603


Related Trials