RecruitingNCT04946721

2177GCCC:ID'Ing tx Targets and Biomarkers for Ocular Surface Disease in Pt w/ oGVHD

2177GCCC: Identifying Novel Treatment Targets and Biomarkers for Ocular Surface Disease in Patients With Ocular Graft vs Host Disease (oGVHD) a Biobank Study


Sponsor

University of Maryland, Baltimore

Enrollment

150 participants

Start Date

Apr 27, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Evaluate and study the immunologic changes to the ocular surface in cancer patients.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Adult patients (≥ 18 years of age) who visit the Eye clinic either in the UMGCCC within the UMD Hospital or the UMD Faculty Physicians Ophthalmology Practice at the UMD Professional Building or satellite locations for initial visits or established visits.
  • The patient must be able to understand and sign and date the informed consent form approved by the IRB.

Exclusion Criteria3

  • Vulnerable populations: neonates, children, prisoners, institutionalized individuals.
  • Inability or refusal to provide informed consent.
  • History of ocular surgery (except refractive surgery or cataract surgery)

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Interventions

DIAGNOSTIC_TESTThe standard care exam and biological specimens' collection

During each visit, in addition to standard of care exams, certain biological specimens ( ocular surface wash, mucocellular material, corneal filaments or impression cytology of conjunctiva, blood or serum) will be collected.


Locations(1)

Geenebaum Cancer Center, University of Maryland Medical Center

Baltimore, Maryland, United States

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NCT04946721


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