RecruitingNot ApplicableNCT04959604

Lymph Node Mapping Via Flourescent Dye in Colon Cancer

Lymph Node Mapping Via the Flourescent Dye ICG in Colon Cancer Through Preoperative Application

Sponsor

Universitätsklinikum Hamburg-Eppendorf

Enrollment

30 participants

Start Date

May 31, 2021

Study Type

INTERVENTIONAL

Conditions

Lymph Node Metastases Colon Carcinoma

Summary

The aim of the study is to evaluate whether lymph nodes draining the region of the carcinoma are located only inside the lines of standard resection or in some percentages are located outside as well. The visualized nodes draining the region of the carcinoma will be correlated to location, fluorescent yes/no and nodal positive/negative. The draining lymph nodes will be visualized using the fluorescent dye indocyanine green. The aim of the study is to evaluate whether lymph nodes draining the region of the carcinoma are located only inside the lines of standard resection or in some percentages are located outside as well. The visualized nodes draining the region of the carcinoma will be correlated to location, fluorescent yes/no and nodal positive/negative. The draining lymph nodes will be visualized using the fluorescent dye indocyanine green.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating whether using a fluorescent (glow-in-the-dark) dye injected near a colon tumor during surgery can help surgeons more accurately identify and remove the nearby lymph nodes — small glands that cancer often spreads to first. Better lymph node mapping could improve the accuracy of cancer staging and treatment decisions. **You may be eligible if...** - You have been diagnosed with colon cancer (confirmed by tissue biopsy) located in the ascending, transverse, descending, or sigmoid colon - You are scheduled for surgical removal of the colon cancer **You may NOT be eligible if...** - You do not wish to participate - You have a cancer type other than adenocarcinoma (the most common colon cancer type) - It is not possible to place an endoscopic (camera-based) marker near your tumor Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREICG-marking endoscopically

Preoperatively the participants will receive an endoscopic marking at four points around the tumour with the fluorescent dye indocyanine green.

Locations(1)

University of Hamburg Medical Institutions

Hamburg, Germany

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NCT04959604

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