Breast Mesh Used in Two-staged Breast Reconstruction

This study is examining whether using a surgical mesh during the first stage of two-stage breast reconstruction after mastectomy leads to better outcomes for women with breast cancer. **You may be eligible if...** - You have been diagnosed with breast cancer and are planning a two-stage breast reconstruction - You are over 18 years old - You have good general health and performance status - You have no evidence of distant (spread) cancer - Your BMI is below 35 - You have minimal or no breast sagging - You have normal blood counts, heart, liver, and kidney function **You may NOT be eligible if...** - Your cancer has spread to other parts of the body, or you have a local recurrence - You have previously had radiation to the same breast or chest wall - You have inflammatory breast cancer or stage IV disease - You have severe allergies or a history of anaphylaxis - You are pregnant, breastfeeding, or planning pregnancy during the study - You have a mental illness or substance abuse problem Talk to your doctor to see if this trial is right for you.