Microbial Restoration in Inflammatory Bowel Diseases

This study is testing whether gut microbiome restoration therapy (a treatment that changes the bacteria living in the gut) can help put active Crohn's disease into remission. **You may be eligible if...** - You have active Crohn's disease confirmed by endoscopy (or bowel ultrasound if the small bowel is hard to reach) within the past 6 months - Your Crohn's disease activity score (CDAI) is between 220 and 450, indicating moderate-to-severe active disease - You also have elevated inflammatory markers (CRP, stool calprotectin, or imaging showing inflammation) - You are willing to attend the study site for regular endoscopic procedures **You may NOT be eligible if...** - You have active fistulas or perianal Crohn's disease - You are pregnant or plan to become pregnant within 12 months - You have a different type of bowel inflammation (not Crohn's) - You have a significant intestinal narrowing (stricture) likely to need surgery - You have a stoma (colostomy or ileostomy) or have had a total colectomy Talk to your doctor to see if this trial is right for you.