RecruitingNot ApplicableNCT06221254

A Smartphone Application for Added Psychological Wellbeing in Crohn's Disease

Israeli IBD Research Nucleus (IIRN) Consortium: COBMINDEX Goes Forward- A Smartphone Application for Added Psychological Wellbeing in Crohn's Disease


Sponsor

Soroka University Medical Center

Enrollment

200 participants

Start Date

Aug 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Psychological intervention by COBMINDEX application to reduce psychological stress among CD patients, fatigue and pain and improve the patients' well being, quality-of-life and disease-coping skills, as well as improvement of the patients' immunological profile and intestinal microbiome.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria7

  • Willingness to participate and signed informed consent
  • Hebrew-speaking
  • Age 18-75
  • Proven diagnosis of Crohn's disease, at least 3 months post-diagnosis
  • Stable medical treatment for the last 3 months
  • Any Harvey Bradshaw Index score
  • Ability to operate a smartphone and cellular application

Exclusion Criteria8

  • Diagnosis of ulcerative colitis or unclassified inflammatory bowel disease
  • Planned surgery for Crohn's disease
  • Surgery for Crohn's disease (excluding drainage of perianal abscess) in the last 3 months
  • Psychiatric disease (schizophrenia, major depression or bipolar disorder)
  • Alcohol or drug dependency (stable medical use of cannabinoids will be allowed)
  • Pregnancy or planned pregnancy during study period
  • Clinically significant comorbidity
  • Former participation in COBMINDEX trials

Interventions

BEHAVIORALCOBMINDEX digital application

COBMINDEX is a Cognitive, behavioral and mindfulness-based stress reduction with daily self-exercise. The intervention comprises of 7 sessions in which stress reduction techniques are learned. In this arm the Patient learns techniques and practices using digital application.

BEHAVIORALHuman therapist (Control)

COBMINDEX is a Cognitive, behavioral and mindfulness-based stress reduction with daily self-exercise. The intervention comprises of 7 sessions in which stress reduction techniques are learned. In this arm the Patient learns techniques from a human therapist (the comperator for learning from the application) and practices using digital application.


Locations(4)

Soroka University Medical Center

Beersheba, Israel

Rambam Health Care Campus i

Haifa, Israel

Belinson Medical Center

Petah Tikva, Israel

Sheba Medical Center

Ramat Gan, Israel

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NCT06221254


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