Early Specialized Cardiovascular Intervention Based on Impedance Cardiography in Locally Advanced Non-small Cell Lung Cancer Patients

This trial is testing whether monitoring heart function with a non-invasive device (impedance cardiography) and stepping in early with heart-protecting treatment can prevent heart damage in lung cancer patients receiving aggressive chemotherapy and radiation. **You may be eligible if...** - You have locally advanced, inoperable non-small cell lung cancer (Stage III) - You are planned to receive chemotherapy and radiation (with or without immunotherapy) - You are between 18 and 75 years old - Your heart output is already showing an abnormality at the start of treatment - You are in good overall health (WHO performance status 0–1) **You may NOT be eligible if...** - You have had a heart attack or unstable chest pain in the past month - You have significant heart, lung, liver, or kidney problems - Your general health status is poor (PS 2–4) Talk to your doctor to see if this trial is right for you.