RecruitingNot ApplicableNCT04993196
Quantitative T1rho Magnetic Resonance Imaging in Healthy Subjects
Sponsor
Chinese University of Hong Kong
Enrollment
30 participants
Start Date
Aug 1, 2021
Study Type
INTERVENTIONAL
Conditions
Summary
T1rho imaging is a new MRI technique that has strong potential in neuroimaging. This technique does not require exogenous contrast agents and has high spatial resolution. In this study we aim to characterise the normal appearance of T1rho in the brain parenchyma in healthy participants. T1rho values will be measured in normal brain structures.
Eligibility
Min Age: 18 Years
Inclusion Criteria1
- \- Male and female volunteers greater than or equal to 18 years of age
Exclusion Criteria3
- Subjects with a contraindication to magnetic resonance imaging such as the presence of metallic implants, claustrophobia and pregnancy.
- Subjects with previous severe allergic or anaphylactoid reaction to a gadolinium contrast agent, or contraindication to contrast gadolinium administration, such severe renal disease or acutely deteriorating renal function, who would be at risk of nephrogenic systemic fibrosis
- Subjects who are unable to tolerate the scan without moving the head as a result of symptoms such as tremor, spasticity, involuntary movements and spasms, cognitive impairment, coughing, and shortness of breath.
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Interventions
DIAGNOSTIC_TESTT1rho imaging
Magnetic Resonance Imaging using T1rho
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04993196
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