RecruitingPhase 2NCT06629090

Brain Blood Vessel Responses to Changes in Blood Flow: Younger Cohort

Cerebrovascular Responses to Acute Hypoperfusion

Sponsor

University of Wisconsin, Madison

Enrollment

36 participants

Start Date

Dec 17, 2025

Study Type

INTERVENTIONAL

Conditions

Magnetic Resonance Imaging Cerebrovascular Circulation

Summary

Brain blood flow will be measured during a simulated postural change test and while breathing increased levels of carbon dioxide using magnetic resonance imaging.

Eligibility

Min Age: 20 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called MRI, a drug called Placebo, and others for people with cerebrovascular circulation and magnetic resonance imaging. The study is currently recruiting participants at 1 location. People eligible for this study include aged 20 Years to 40 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEMRI

Participants will undergo an MRI scan while performing breathing and simulated postural change tasks.

DRUGPrazosin

A dose of prazosin will be administered based on body weight

DRUGPlacebo

Oral placebo

Locations(1)

University of Wisconsin

Madison, Wisconsin, United States

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NCT06629090

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