Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?

This study is examining whether patients with a brain drain tube (external ventricular drain, or EVD) need prophylactic (preventive) antibiotics to avoid infection when the drain is inserted. EVDs are placed in people who have had brain bleeds or strokes and need the fluid around their brain drained. The study compares antibiotic-coated drains with and without additional antibiotic drugs. You may be eligible if: - You are 18 years or older - You have been diagnosed with a subarachnoid hemorrhage, intracerebral hemorrhage, or acute ischemic stroke - You require an external ventricular drain (EVD) for your condition You may NOT be eligible if: - You were already on antibiotics within the week before admission - You have a low white blood cell count (leukopenia) at baseline - You show signs of meningitis, ventriculitis, or another infection at admission - You are pregnant or a prisoner - You are under 18 years old Talk to your doctor to see if this trial is right for you.