Hydrocephalus Clinical Trials

41 recruitingLast updated: June 18, 2026

There are 41 actively recruiting hydrocephalus clinical trials across 15 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3. Top locations include Beijing, Beijing Municipality, China, Houston, Texas, United States, Tampa, Florida, United States. Updated daily from ClinicalTrials.gov.


Hydrocephalus Trials at a Glance

41 actively recruiting trials for hydrocephalus are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 14 trials, with the heaviest enrollment activity in Beijing, Houston, and Tampa. Lead sponsors running hydrocephalus studies include Rhaeos, Inc., Beijing Tiantan Hospital, and University of South Florida.

Browse hydrocephalus trials by phase

Treatments under study

About Hydrocephalus Clinical Trials

Looking for clinical trials for Hydrocephalus? There are currently 23 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hydrocephalus trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hydrocephalus clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 41 trials

Recruiting
Not Applicable

Ultrasound (US) Guided External Ventricular Catheter Placement

Hydrocephalus
Milton S. Hershey Medical Center10 enrolled1 locationNCT06253858
Recruiting
Not Applicable

Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

Normal Pressure Hydrocephalus
CereVasc Inc230 enrolled31 locationsNCT06498960
Recruiting
Not Applicable

Examining the Feasibility of Using Pressure Gradient Regulated Automated Cerebral Spinal Fluid Drainage During External Lumbar Drain Trials

NPH (Normal Pressure Hydrocephalus)
University of Texas Southwestern Medical Center10 enrolled1 locationNCT07494812
Recruiting

Assessment of ShuntCheck Performance Characteristics in Asymptomatic Patients With Normal Pressure Hydrocephalus

Hydrocephalus, Normal Pressure
University of South Florida50 enrolled1 locationNCT04011566
Recruiting

Diagnostic Accuracy of ShuntCheck Compared to Radionuclide Shunt: Patency in Patients With Normal Pressure Hydrocephalus

Hydrocephalus, Normal Pressure
University of South Florida20 enrolled1 locationNCT04309487
Recruiting

HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)

Pediatric Hydrocephalus
University of Utah1,400 enrolled14 locationsNCT00670735
Recruiting

European Study of Prodromal iNPH

HydrocephalusNormal Pressure Hydrocephalus
Johan Virhammar140 enrolled7 locationsNCT05910944
Recruiting
Not Applicable

Multi-omics Research of Idopathic Normal Pressure Hydrocephalus (iNPH)

Idiopathic Normal Pressure Hydrocephalus
Second Affiliated Hospital, School of Medicine, Zhejiang University40 enrolled1 locationNCT04998175
Recruiting

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

Cystic FibrosisHuntington DiseaseSickle Cell Disease+12 more
Assistance Publique - Hôpitaux de Paris550 enrolled1 locationNCT06147414
Recruiting
Not Applicable

Normal Pressure Hydrocephalus and Sleep Apnea

Sleep ApneaNormal Pressure HydrocephalusCerebrospinal Fluid Shunt Occlusion
University of Valencia30 enrolled1 locationNCT04471740
Recruiting
Phase 2

CEUS Evaluation of Hydrocephalus in Neonates and Infants

Hydrocephalus in InfantsHydrocephalus Acquired
Children's Hospital of Philadelphia20 enrolled1 locationNCT06693752
Recruiting

Neurosurgical Outcome Network

DepressionTrigeminal NeuralgiaObsessive-Compulsive Disorder+20 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta4,500 enrolled27 locationsNCT06724029
Recruiting

White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)

Normal Pressure Hydrocephalus
Imperial College London100 enrolled1 locationNCT07103681
Recruiting
Not Applicable

EVD Drainage Data and Intracranial Pressure (ICP) Measurements

Hydrocephalus
Baylor College of Medicine24 enrolled1 locationNCT05546996
Recruiting

Shunt-dependency After aSAH - Role of Early Hyperglycaemia in CSF and Blood

HydrocephalusHyperglycemiaAneurysm, Ruptured
Isabel Hostettler160 enrolled3 locationsNCT06486909
Recruiting

NIRS Monitoring in Premature Infants

Premature infantsHydrocephalusHemorrhage+1 more
Boston Children's Hospital70 enrolled3 locationsNCT02601339
Recruiting
Not Applicable

Flow Detection in Open and Closed Shunt Valve Periods

Hydrocephalus
Rhaeos, Inc.55 enrolled1 locationNCT07478926
Recruiting

Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)

Parkinson's DiseaseParkinsonismFreezing of Gait+2 more
Tianjin Huanhu Hospital700 enrolled1 locationNCT07386015
Recruiting

Crystallization of LA and Adjuvant Mixtures in Cerebrospinal Fluid

Hydrocephalus
Medical University Innsbruck10 enrolled1 locationNCT07442929
Recruiting

Integrated Multimodal Assessment to Optimize Diagnosis and Surgical Selection in Idiopathic Normal Pressure Hydrocephalus

Idiopathic Normal Pressure Hydrocephalus
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico116 enrolled2 locationsNCT07427836