ConsideRAte Study - Splenic Stimulation for RA

This study tests a device that stimulates the spleen (an organ involved in immune function) through a small implant, as a new way to treat rheumatoid arthritis (RA) — a condition where the immune system attacks the joints causing pain, swelling, and damage — in people who have not responded well to multiple medications. **You may be eligible if...** - You have been diagnosed with rheumatoid arthritis for at least 6 months - You are between 22 and 75 years old - Your RA is currently active and causing symptoms - You have tried at least 2 biologic medications and/or JAK inhibitors (including at least one TNF inhibitor) without adequate relief **You may NOT be eligible if...** - You have active or latent tuberculosis - You have HIV, active hepatitis B or C - You have had your vagus nerve cut (vagotomy) in the past - You have a serious psychiatric condition or active substance abuse Talk to your doctor to see if this trial is right for you.