RecruitingPhase 1NCT07171983

A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986454 in Participants With Rheumatoid Arthritis

A 2-Part, Phase 1b Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-986454 in Participants With Rheumatoid Arthritis

Sponsor

Bristol-Myers Squibb

Enrollment

46 participants

Start Date

Feb 27, 2026

Study Type

INTERVENTIONAL

Conditions

Rheumatoid Arthritis

Summary

The purpose of this study is to evaluate the safety, tolerability, and drug levels of BMS-986454 in participants with Rheumatoid Arthritis

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called BMS-986454 and Placebo for people with rheumatoid arthritis. The study is currently recruiting participants at 9 locations. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGBMS-986454

Specified dose on specified days

OTHERPlacebo

Specified dose on specified days

Locations(9)

Nizams Institute Of Medical Sciences

Hyderabad, Andhra Pradesh, India

Local Institution - 0004

Ahmedabad, Gujarat, India

Local Institution - 0003

Bangalore, Karnataka, India

Local Institution - 0009

Mysuru, Karnataka, India

All India Institute of Medical Sciences (AIIMS) - Nagpur

Nagpur, Maharashtra, India

Life Point Mutispecialty Hospital Pvt. Ltd.

Pune, Maharashtra, India

Kalinga Institute of Medical Sciences- Bhubaneswar

Bhubaneswar, Odisha, India

Local Institution - 0002

Hyderabad, Telangana, India

Krishna Institute of Medical Sciences Limited

Secunderabad, Telangana, India

View Full Details on ClinicalTrials.gov

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NCT07171983

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