RecruitingNCT05008081

The CATALINA Study

An International Multi-centre Prospective Cohort Study in Patients Hospitalized for an Acute Exacerbation of COPD


Sponsor

Wim Janssens

Enrollment

1,000 participants

Start Date

Oct 25, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The CATALINA study is a prospective cohort study embedded within CICERO (Collaboration In COPD ExaceRbatiOns, a European Respiratory Society supported Clinical Research Collaboration), designed to collect standardised, longitudinal clinical data and biological samples in 20 centres across Europe and beyond.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Age 18 years and older
  • Established diagnosis of COPD by medical doctor (based on clinical history OR pulmonary function test with an FEV1/FVC \< 0.7)
  • Current hospitalization with suspicion of an acute exacerbation of COPD (AECOPD)
  • Inclusion within 48 hours post hospital admission
  • Voluntary written informed consent of the participant or his/her representative obtained prior to any study procedure

Exclusion Criteria3

  • Patients unwilling or unable to comply with study procedures
  • Patients not requiring treatment with systemic corticosteroids, antibiotics or both as a minimum therapy for the index AECOPD
  • Patients with a confirmed positive test result for COVID19, or those highly suspected based on clinical examination

Locations(18)

Kepler University Hospital

Linz, Austria

CHU St-Pierre Brussels

Brussels, Belgium

UZ Leuven

Leuven, Belgium

CHU UCL Namur Site Godinne

Yvoir, Belgium

CHU de Lille

Lille, France

Cochin Hospital

Paris, France

LungenClinic

Großhansdorf, Germany

Klinikum Itzehoe

Itzehoe, Germany

University Medical Centre of Gießen & Marburg

Marburg, Germany

University Hospital of Ferrara

Ferrara, Italy

UMC Groningen

Groningen, Netherlands

Maastricht University Medical Hospital

Maastricht, Netherlands

Hospital Clinic de Barcelona

Barcelona, Spain

Sahlgrenska University Hospital

Gothenburg, Sweden

Glenfield Hospital

Leicester, United Kingdom

Guy's Saint Thomas

London, United Kingdom

Royal Brompton Hospital

London, United Kingdom

Churchil Hospital

Oxford, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT05008081


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