RecruitingNCT05010603

Late Onset Alzheimer's Disease


Sponsor

Columbia University

Enrollment

10,000 participants

Start Date

Nov 15, 2016

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this study is to is to focus on the genetic influences on Alzheimer's Disease (AD) risk. The investigators are looking for families and/or individuals (affected or unaffected) of any ethic background (African American, Caucasian, and Hispanics) with a family history of AD and willing to participate.


Eligibility

Min Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This study is researching the genetics behind late-onset Alzheimer's disease and related memory disorders. Researchers want to understand why these diseases run in families by studying patients alongside their relatives. **You may be eligible if...** - You have been diagnosed with Alzheimer's disease, Frontotemporal Dementia (FTD), or Lewy Body Dementia - You have a living sibling who has probable or possible Alzheimer's disease - You have at least one more relative with Alzheimer's disease (who got it at age 50 or older) or an unaffected relative aged 60 or older - You have a close companion or family member who can serve as an informant - You can consent yourself, or have a family member who can consent on your behalf **You may NOT be eligible if...** - No appropriate informant (someone who knows you well) can be identified - Your diagnosis is uncertain - Another condition could explain your symptoms - You are unwilling to participate - You have no living sibling with Alzheimer's or a related disorder (unless your diagnosis is sporadic FTD or sporadic LBD) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

GENETICBlood Draw

Collection of blood samples for genetic testing

OTHERLate Onset Alzheimer's Disease (LOAD) Neuropsychological Battery Test

Memory Test


Locations(12)

University of Washington

Washington D.C., District of Columbia, United States

University of Miami

Miami, Florida, United States

Rush University

Aurora, Illinois, United States

Indiana University

Bloomington, Indiana, United States

NCRAD at Indiana University

Indianapolis, Indiana, United States

Mayo Clinic

Rochester, Minnesota, United States

Joanne Norton

St Louis, Missouri, United States

Columbia University Irving Medical Center

New York, New York, United States

North Carolina State University

Raleigh, North Carolina, United States

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

University of Texas Southwestern

Dallas, Texas, United States

University of Washington

Seattle, Washington, United States

View Full Details on ClinicalTrials.gov

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NCT05010603


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