RecruitingNCT05025774

Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise

Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant Bronchopulmonary Dysplasia (BPD, Also Known as Chronic Lung Disease of Prematurity) Through Exercise (FLASHLITE)

Sponsor

Masonic Cancer Center, University of Minnesota

Enrollment

90 participants

Start Date

Mar 14, 2025

Study Type

OBSERVATIONAL

Conditions

Acute Lymphoblastic Leukemia Chronic Obstructive Pulmonary Disease Chronic Lung Disease Heart Transplant

Summary

This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))

Eligibility

Min Age: 8 YearsMax Age: 25 Years

Plain Language Summary

Simplified for easier understanding

This study tests a supervised exercise program in young people (ages 8–25) who are survivors of childhood leukemia, heart transplant recipients, or who have chronic lung disease from premature birth. It measures how exercise affects their fitness, lung function, and overall health compared to healthy peers. **You may be eligible if...** - You are between 8–25 years old - You are a survivor of acute lymphoblastic leukemia (ALL), or you live with a transplanted heart, or you have chronic lung disease from being born premature - You can walk without assistance and are at least 48 inches tall - You speak English - (For ALL survivors) You finished treatment at least 3 months ago **You may NOT be eligible if...** - You are an ALL survivor who received radiation to the head or had a bone marrow transplant - You are pregnant - Your blood oxygen levels are too low - Your doctor believes the exercise testing is not safe for you Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERPhysical activity

Participant Reported Physical Activity and Outcomes (completed via REDCap or on paper)

Locations(1)

Masonic Cancer Center

Minneapolis, Minnesota, United States

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NCT05025774

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