RecruitingPhase 3NCT05028140

Efficacy and Safety of Piemonte Association in the Treatment of Type II Diabetes Mellitus

National, Multicenter, Randomized, Double-blind, Triple-dummy, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Piemonte Association in the Treatment of Type II Diabetes Mellitus


Sponsor

EMS

Enrollment

480 participants

Start Date

Oct 8, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the efficacy and safety of Piemonte association in the treatment of type 2 diabetes mellitus


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria2

  • Ability to confirm voluntary participation and agree to all trial purposes by signing and dating the consent form;
  • Diagnosis of type II diabetes mellitus, and who did not reach the therapeutic goal of HbA1c with previous dietary, physical exercise, and previous therapies at stable doses within 3 months.

Exclusion Criteria6

  • Any clinical and laboratory findings that, in the judgment of the investigator, may interfere with the safety of participants;
  • History of alcohol abuse or illicit drug use;
  • Participation in a clinical trial in the year prior to this study;
  • Pregnancy or risk of pregnacy and lactating participants;
  • Known hypersensitivity to any of the formula compounds;
  • Type 1 diabetes.

Interventions

DRUGPIEMONTE

Piemonte association 1 coated tablet once a day

OTHERPIEMONTE PLACEBO

Placebo of Piemonte association 1 coated tablet once a day

DRUGEMPAGLIFLOZIN

Empagliflozin 25 mg 1 coated tablet once a day

OTHERPLACEBO EMPAGLIFLOZIN

Placebo of empagliflozin 25 mg 1 coated tablet once a day

DRUGPIOGLITAZONE

Pioglitazone 30 mg 1 tablet once a day

OTHERPLACEBO PIOGLITAZONE

Placebo of pioglitazone 30 mg 1 tablet once a day


Locations(1)

EMS

Hortolândia, São Paulo, Brazil

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NCT05028140


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