RecruitingNot ApplicableNCT06385626

The Effects of Raspberry Leaf Tea on Blood Glucose Control

The Effects of Raspberry Leaf Tea on Blood Glucose Control in Healthy Adults


Sponsor

University of Reading

Enrollment

20 participants

Start Date

Dec 18, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of the present clinical trial is to assess how raspberry leaf polyphenols impact on postprandial glucose and insulin levels in healthy individuals consuming sucrose. The questions the project will address: * Do raspberry leaf polyphenols lower sucrose-induced increases in plasma glucose in humans? * Do these polyphenols mediate these effects by inhibiting digestion of sucrose or the absorption of glucose. 20 healthy adults will be recruited between the ages of 18-65 years who are non-smokers and not taking certain types of medication (e.g., drugs from a GP for high blood pressure, high blood fats, inflammatory conditions, and depression) or dietary supplements (e.g., cholesterol-lowering spreads, fish oil, probiotics, prebiotics, and natural laxatives), antibiotics in the last three months or if they used any drugs or supplements that could affect their blood glucose or lipid metabolism. No abnormal results for liver function tests, renal function tests, and lipid profile tests. If they have food allergies or consume more than 14 units of alcohol per week (i.e., to help they calculate a alcohol intake, one standard glass of wine (175 ml) or one pint of regular lager is equivalent to just over two units of alcohol), frequently travel for work or are participating in another intervention study, they will not be able to participate. Women who are pregnant or lactating or planning a pregnancy in the next six months will also not be able to take part, not use herbal medicines for at least the previous three months, not be on a weight loss program six months before screening, not involved in clinical trials six months before the screening, and not having severe cardiac, hepatic, or renal function impairment. Not Sufferers of chronic illnesses, not Individuals with food allergies, not people with coeliac disease. They will be asked to attend a four-study visit after an eight-hour overnight fast. Volunteers will be asked to consume 50 g of carbohydrate powder (sucrose and glucose) with or without 10 g of raspberry leaf tea, which will be dissolved in 300 mL of warm water during four visits (every month). Blood samples will be taken at intervals for a period of two hours after the consumption of raspberry leaf or control. Blood glucose and insulin levels will be tested 15 minutes before, at 15,30,60,90, and 120 minutes after carbohydrate intake.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether drinking raspberry leaf tea can help control blood sugar levels in healthy adults, as part of research into natural dietary supplements that may support metabolic health. **You may be eligible if...** - You are between 18 and 65 years old - Your fasting blood sugar is below 5.5 mmol/L (normal range) - Your BMI is 34.9 or below - You are a non-smoker - You are not pregnant or breastfeeding - You have not used herbal medicines in the past 3 months **You may NOT be eligible if...** - You smoke, are pregnant, or are breastfeeding - You have diabetes or prediabetes - You have chronic illness, celiac disease, or food allergies - You have severe heart, liver, or kidney problems - You are involved in a weight loss program or another clinical trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTRaspberry leaf tea

10 g of raspberry leaf tea


Locations(1)

Hugh Sinclair Unit of Human Nutrition, University of Reading

Reading, Berkshire, United Kingdom

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NCT06385626


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