RecruitingPhase 4NCT05029726

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

Randomized, Placebo-controlled Trial of Erector Spinae Plane Blocks (ESPB) for Perioperative Pain Management for Minimally Invasive (MIS) Lumbar Spine Surgery

Sponsor

John O'Toole

Enrollment

125 participants

Start Date

Feb 1, 2022

Study Type

INTERVENTIONAL

Conditions

Lumbar Radiculopathy Degenerative Disc Disease Lumbar Spinal Stenosis Lumbar Disc Herniation Lumbar Spondylolisthesis Lumbar Spondylosis Lumbar Spine Instability Synovial Cyst Degenerative Spondylolisthesis Degenerative Intervertebral Discs

Summary

Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids. Reducing the need for opiate analgesics in the post-operative setting has become a high priority in minimizing long-term opioid use in surgical patients. This study will serve to demonstrate the efficacy of the addition of regional analgesic techniques in reducing post-operative opioid requirements in patients undergoing common lumbar spinal surgical procedures.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine and a drug called normal saline for people with degenerative disc disease, degenerative intervertebral discs, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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