RecruitingNCT05030220

Testosterone Levels and Cutibacterium

Association Between Serum Testosterone Levels and Cutibacterium Culture Positivity During Shoulder Arthroplasty

Sponsor

University of Washington

Enrollment

300 participants

Start Date

Jul 1, 2020

Study Type

OBSERVATIONAL

Conditions

Arthroplasty, Replacement, Shoulder

Summary

Phase 1: In 51 patients undergoing shoulder arthroplasties, total serum testosterone, free testosterone and sex hormone binding globulin levels obtained in the clinic before surgery were correlated with the levels of Cutibacterium on the skin in clinic, in the operating room prior to surgery, and in the skin incision. Phase 2: The investigators wish to determine if preoperative serum testosterone levels are associated with risk for shoulder PJI (periprosthetic joint infection) in patients undergoing primary shoulder arthroplasty. Also to determine if preoperative serum testosterone levels are predictive of bacterial load of deep tissue cultures taken at the time of revision shoulder arthroplasty in patients undergoing primary shoulder arthroplasty.

Eligibility

Min Age: 18 YearsMax Age: 89 Years

Plain Language Summary

Simplified for easier understanding

This study examines whether testosterone levels in the body are linked to the presence of Cutibacterium (a type of skin bacteria) in patients having shoulder replacement surgery. This bacteria can sometimes cause post-surgical infections. You may be eligible if: - You are 18 to 89 years old - You are scheduled for elective shoulder replacement surgery - You are fluent in English You may NOT be eligible if: - You have a history of shoulder joint infection (septic arthritis) - You have taken antibiotics in the last 3 months - You have recently been treated for acne - You are not fluent in English Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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