RecruitingNCT05030220

Testosterone Levels and Cutibacterium

Association Between Serum Testosterone Levels and Cutibacterium Culture Positivity During Shoulder Arthroplasty


Sponsor

University of Washington

Enrollment

300 participants

Start Date

Jul 1, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

Phase 1: In 51 patients undergoing shoulder arthroplasties, total serum testosterone, free testosterone and sex hormone binding globulin levels obtained in the clinic before surgery were correlated with the levels of Cutibacterium on the skin in clinic, in the operating room prior to surgery, and in the skin incision. Phase 2: The investigators wish to determine if preoperative serum testosterone levels are associated with risk for shoulder PJI (periprosthetic joint infection) in patients undergoing primary shoulder arthroplasty. Also to determine if preoperative serum testosterone levels are predictive of bacterial load of deep tissue cultures taken at the time of revision shoulder arthroplasty in patients undergoing primary shoulder arthroplasty.


Eligibility

Min Age: 18 YearsMax Age: 89 Years

Inclusion Criteria2

  • Patients having elective shoulder arthroplasty
  • Patients having elective shoulder arthroplasty

Exclusion Criteria5

  • history of shoulder septic arthritis
  • antibiotic use within 3 months prior to surgery
  • recent treatment for acne
  • Lacked fluency in English
  • Lacked fluency in English

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Locations(1)

University of Washington

Seattle, Washington, United States

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NCT05030220


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