Testosterone Levels and Cutibacterium
Association Between Serum Testosterone Levels and Cutibacterium Culture Positivity During Shoulder Arthroplasty
University of Washington
300 participants
Jul 1, 2020
OBSERVATIONAL
Conditions
Summary
Phase 1: In 51 patients undergoing shoulder arthroplasties, total serum testosterone, free testosterone and sex hormone binding globulin levels obtained in the clinic before surgery were correlated with the levels of Cutibacterium on the skin in clinic, in the operating room prior to surgery, and in the skin incision. Phase 2: The investigators wish to determine if preoperative serum testosterone levels are associated with risk for shoulder PJI (periprosthetic joint infection) in patients undergoing primary shoulder arthroplasty. Also to determine if preoperative serum testosterone levels are predictive of bacterial load of deep tissue cultures taken at the time of revision shoulder arthroplasty in patients undergoing primary shoulder arthroplasty.
Eligibility
Inclusion Criteria2
- Patients having elective shoulder arthroplasty
- Patients having elective shoulder arthroplasty
Exclusion Criteria5
- history of shoulder septic arthritis
- antibiotic use within 3 months prior to surgery
- recent treatment for acne
- Lacked fluency in English
- Lacked fluency in English
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Locations(1)
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NCT05030220