RecruitingNot ApplicableNCT05036629

Development of MRI Protocols and Associated Neuro-physiological Explorations in Healthy and Pathological Subjects

Sponsor

University Hospital, Grenoble

Enrollment

600 participants

Start Date

Sep 9, 2021

Study Type

INTERVENTIONAL

Conditions

MRI Sequence Optimization Physiological Measurement

Summary

IRMaGe is a Joint Service Unit (UMS) which provides users of brain exploration equipment (clinical MRI and preclinical, TMS, EEG, NIRS and metabolomics). The methods available on this equipment are intended to evolve according to the most recent discoveries and this protocol aims to frame the developments necessary around clinical MRI for IRMaGe can continue to offer tools at the cutting edge of technology.

Eligibility

Min Age: 18 Years

Inclusion Criteria5

Participants with normal or corrected vision
Participants affiliated to a social security scheme or beneficiaries of such a scheme
Participants with French as their mother tongue
Participants who have given the signed informed consent before carrying out any procedure related to the study.
Volunteer patients will be recruited as part of their follow-up at the CHU. Their pathology will be in agreement with that of the research protocol to be optimized.

Exclusion Criteria10

Criteria relating to contraindications to the explorations provided for by the MRI protocol:
metallic glitter in the eyes
retinal operation
claustrophobia
wearer of pacemaker or cardiac defribrillator or vascular clip or prosthesis cardiac or insulin pump or implanted device to deliver medication or hearing implant or prosthesis or vascular shunt or paragraph or screws, plate metal or tattoo or piercing or implanted metal object or lead shot hunt
Alcohol ingestion before the examination
Pregnant, lactating and parturient women
Major protected by law
Participants under administrative or judicial supervision
Participation in another ongoing study if the study may interfere with participation in the protocol MAP-IRMaGe.

Interventions

DEVICEMRI Protocol

Eye-tracker Eyelink (eye movements) BIOPAC : (electrodermal resistance) INVIVO Precess : breathing, arterial pressure, pulse, * NIRS Oxymon artinis medical system * tES (transcranial electrical stimulation, Neuroelectrics)