ETASCAN Project: ETAS Project 2

Exclusion Criteria26

• Smoking
• Having food allergies
• Following restrictive and/or unbalanced diets (Appendix 6: Are you vegetarian or vegan? Yes / No; Are you currently on a weight-reducing or other special diet? Yes/No If 'Yes', please give details.)
• Being diagnosed with any psychiatric or neurologic conditions (e.g. schizophrenia, depression, dementia) including eating disorders
• Being diagnosed with any cardiometabolic diseases (including type II diabetes and cardiovascular disease), or hypertension or thrombosis related disorders or suffer from thyroid disease
• Currently taking anticoagulants, antiplatelet medication, antidepressants, proton-pump inhibitors
• Currently consuming prebiotic or probiotic supplements
• Continuous antibiotic use for > 3 days within 1 month prior to enrolment
• Continuous use of weight-loss drug for > 1 month before screening
• Having a significant gastrointestinal (GI) condition affecting absorption including (but not limited to) inflammatory bowel disease; total colectomy or bariatric surgery; irritable bowel disease; end stage renal disease; active cancer, or treatment for any cancer, in last 3 years
• History of claustrophobia
• Fitted with a pacemaker or artificial heart valve
• Have active implants, such as cochlear, ocular, or penile implant
• Experience of metal fragments e.g. shrapnel in your eyes or any other part of your body
• Drug infusion pump installed
• Have any surgically implanted metal in any part of your body, other than dental fillings and crowns (e.g. joint replacement or bone re-construction)
• Have had any surgery that might have involved metal implants
• Current or historical experience of epilepsy
• Have stimulators for nerves, brain or bone installed
• Have an intrauterine contraceptive device installed (IUD)
• Wear transdermal patches containing metal
• Wear a filling, crown, dental post (entirely within the tooth) associated with root canal treatment, retainer, bridge or braces
• For scanning, would need to remove coloured contact lenses, nail polish and makeup.
• Hearing aid wearer
• Body piercings that you cannot or will not remove for the scanning session
• Have tattoos or permanent makeup