RecruitingNot ApplicableNCT05051254

Respiratory Muscles and Work of Breathing in Children


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

550 participants

Start Date

Jan 19, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Respiratory muscle testing allows a quantitative assessment of inspiratory and expiratory muscles in children of any age with primary or secondary respiratory muscle impairment, in order to better understand the pathophysiology of respiratory impairment and guide therapeutic management. The use of an invasive technique (esogastric probe) makes it possible to specifically explore the diaphragm, the accessory inspiratory muscles and the expiratory muscles in order to detect dysfunction or paralysis of these muscles, and to estimate the work of breathing in order to better guide the respiratory management. The primary objective of the study is to evaluate the respiratory effort in children with primary or secondary impairment of the respiratory muscles during spontaneous breathing or during mechanical ventilation.


Eligibility

Min Age: 0 YearsMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Esogastric pressure measurement for people with cardiac diseases, congenital diaphragmatic hernia, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHEREsogastric pressure measurement

Measurement of work of breathing and respiratory muscles strength using an esogastric catheter. One measurement or before and after (6 months and 1 year) the initiation of a pharmacological treatment in order to assess the effect of the treatment on respiratory muscle function.


Locations(1)

Hôpital Necker-Enfants Malades

Paris, France

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NCT05051254


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