Scoliosis Clinical Trials

119 recruitingLast updated: June 20, 2026

There are 119 actively recruiting scoliosis clinical trials across 28 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2. Top locations include New York, New York, United States, San Francisco, California, United States, Palo Alto, California, United States. Updated daily from ClinicalTrials.gov.


Scoliosis Trials at a Glance

119 actively recruiting trials for scoliosis are listed on ClinicalTrialsFinder across 6 cities in 28 countries. The largest study group is Not Applicable with 64 trials, with the heaviest enrollment activity in New York, San Francisco, and Palo Alto. Lead sponsors running scoliosis studies include The Hong Kong Polytechnic University, Second Affiliated Hospital of Wenzhou Medical University, and International Spine Study Group Foundation.

Browse scoliosis trials by phase

Treatments under study

About Scoliosis Clinical Trials

Looking for clinical trials for Scoliosis? There are currently 28 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Scoliosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Scoliosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 119 trials

Recruiting

UNderstanding the Causes Of Idiopathic Scoliosis Through the Longitudinal Analysis of Proteomic Markers: the UNCOIL Study

Adolescent Idiopathic Scoliosis (AIS)Neuromuscular Scoliosis
University of Colorado, Denver500 enrolled1 locationNCT07634627
Recruiting

The Effect of Peloidotherapy in Young Adults Undergoing Physical Therapy Scoliosis Specific Exercises (PSSE)

Spine DeformityPeloidotherapyAdult Scoliosis
Gaziosmanpasa Research and Education Hospital54 enrolled1 locationNCT07459400
Recruiting

Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Complex

HyperkyphosisHyperlordosisCongenital Scoliosis+2 more
Aesculap AG200 enrolled2 locationsNCT05281757
Recruiting
Not Applicable

Rethinking Rigidity: Development of a 3D-Printed Scoliosis Brace With Varying Flexibility

Scoliosis Idiopathic Adolescent Treatment
Baylor College of Medicine5 enrolled2 locationsNCT06785207
Recruiting
Not Applicable

A Study to Evaluate a New Semi-rigid Brace, the RESILIENT Brace by Thinks Works, as a Way to Limit Curve Worsening in Kids With Idiopathic Scoliosis.

Idiopathic Scoliosis
Thinks Works, PBC30 enrolled1 locationNCT07574632
Recruiting
Not Applicable

Characterization of Visual Perception Impairments in Patients With Idiopathic Scoliosis

Idiopathic Scoliosis
Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française70 enrolled1 locationNCT07356999
Recruiting
Phase 4

The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction

Scoliosis Idiopathic Adolescent
Poznan University of Medical Sciences60 enrolled1 locationNCT06789029
Recruiting

The BRIDGE Pain Study

Pectus excavatumMusculoskeletal PainChronic Pain+4 more
Children's Hospital Medical Center, Cincinnati600 enrolled1 locationNCT07602595
Recruiting
Not Applicable

Effect of Vitamin A Supplementation on Idiopathic Scoliosis

Vitamin A deficiencyIdiopathic Scoliosis
Second Affiliated Hospital of Wenzhou Medical University140 enrolled1 locationNCT07335991
Recruiting
Not Applicable

Effect of Bright Light Therapy on Idiopathic Scoliosis

Idiopathic ScoliosisDelayed Sleep PhaseEveningness
Second Affiliated Hospital of Wenzhou Medical University120 enrolled1 locationNCT07424703
Recruiting
Not Applicable

Effect of Adenotonsillectomy on Spinal Curve Magnitude in Children With Sleep-Disordered Breathing

Sleep-disordered breathing (SDB)Idiopathic ScoliosisObstructive Sleep Apnea (OSA)
Second Affiliated Hospital of Wenzhou Medical University160 enrolled1 locationNCT07332780
Recruiting
Not Applicable

The Adult Degenerative Scoliosis Exercise Trial (Pilot Study)

Degenerative Scoliosis
University of Alberta20 enrolled1 locationNCT03862417
Recruiting

Cyberchondria in Adolescents With Idiopathic Scoliosis

Scoliosis Idiopathic AdolescentCyberchondria
Izmir Democracy University100 enrolled1 locationNCT07481071
Recruiting
Not Applicable

Support System Design for Adolescent Scoliosis Orthosis Wear

Adolescent Idiopathic Scoliosis (AIS)Adherence
Shanghai Jiao Tong University School of Medicine18 enrolled1 locationNCT07574229
Recruiting

Effect of Adult Spinal Deformity Surgery on Functional Reach

ScoliosisScoliosis Kyphosis
University of Kansas Medical Center30 enrolled1 locationNCT06258161
Recruiting
Phase 3

Evaluation of Analgesia for Spine Fusion Elective Surgery in Children

Idiopathic Scoliosis
Senthil Sadhasivam500 enrolled2 locationsNCT06626503
Recruiting
Phase 3

The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery

Adolescent Idiopathic ScoliosisAdolescent Idiopathic Scoliosis (AIS)Neuromuscular Scoliosis
University of California, San Francisco42 enrolled1 locationNCT07561827
Recruiting
Not Applicable

Machine Learning Prediction of Disease Progression in Adolescent Idiopathic Scoliosis

Adolescence Idiopathic Scoliosis
Istanbul University30 enrolled1 locationNCT07556042
Recruiting

Scoliosis Shared Decision Making

Scoliosis
Mayo Clinic25 enrolled1 locationNCT03107533
Recruiting
Not Applicable

Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

Spinal Muscular AtrophyScoliosisSpine Deformity
Alcyone Therapeutics, Inc90 enrolled21 locationsNCT05866419