Contrast Enhanced Spectral Mammography for the Evaluation of Pathologic Nipple Discharge

This study tests a special type of mammogram — called contrast-enhanced spectral mammography (CESM) — to see how well it finds the cause of nipple discharge (fluid leaking from the nipple). Doctors inject a small amount of contrast dye through an IV to help highlight abnormal areas in the breast. **You may be eligible if...** - You are a woman aged 25–85 - You are being evaluated for nipple discharge as a main or accompanying symptom - You are willing to have an IV placed and receive contrast dye **You may NOT be eligible if...** - You have had an allergic reaction to contrast dye (iodine-based) - You have kidney problems - You are pregnant or breastfeeding, or were within the last 6 months - You had breast surgery or a breast biopsy near the nipple within the last 2–6 months - You had a breast MRI within the last 2 years - You have known breast cancer or an active infection in the breast Talk to your doctor to see if this trial is right for you.