RecruitingPhase 3NCT05058287

Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

Topical Epidural Steroid Usage in Patients Undergoing Posterior Lumbar Decompression: A Randomized Control Trial


Sponsor

Hospital for Special Surgery, New York

Enrollment

150 participants

Start Date

Nov 5, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

This study seeks to evaluate the impact of intra-operative topical epidural steroid usage in patients undergoing 1-2 level lumbar laminectomy. The study will examine post-operative opioid usage, length of stay, return to work, and patient reported outcomes following these procedures.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria2

  • Patients scheduled to undergo 1 to 2 level laminectomy
  • Between the ages of 18-85

Exclusion Criteria6

  • Minimally invasive surgery
  • Prior daily opioid usage within 6 months.
  • Use of concomitant procedures such as spinal fusion, revision procedure at the same level.
  • History of a chronic pain syndrome, uncontrolled diabetes defined as A1C \> 6.5, immunocompromised condition such as active cancer treatment, history of transplant, benign prostatic hyperplasia or history of urinary retention, and other conditions which require chronic steroid therapy or immunosuppressants.
  • Non-English speakers
  • Patients allergic to Depo-Medrol and/or glucocorticoids, or other steroids

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGDepo-Medrol 40Mg/Ml Suspension for Injection

40mg Depo-Medrol mixed with hemostatic matrix

DRUGPlacebo

1 mL of sterile normal saline mixed with hemostatic matrix


Locations(1)

Hospital for Special Surgery

New York, New York, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05058287


Related Trials