RecruitingNCT05079399

Biomarker of Diabetic Retinopathy

Sponsor

Indiana University

Enrollment

192 participants

Start Date

Jan 1, 2022

Study Type

OBSERVATIONAL

Conditions

Diabetic Retinopathy

Summary

Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Ability to cooperate with imaging procedures.
Health status: established type 2 diabetes
No history of panretinal photocoagulation (PRP)
No history of treatment with intravitreal agents for past 12 months

Exclusion Criteria8

Previous or current malignancy
Acute or chronic infection (HIV, hepatitis B or C, tuberculosis)
Cerebral vascular accident or cerebral vascular procedure
Current pregnancy
History of organ transplantation
Presence of a graft (to avoid any effect of the graft)
History of previous vitrectomy
Subjects with a history of age-related macular degeneration age-related macular degeneration (AMD), glaucoma, uveitis, and branched or central vein occlusion.