Diabetic Retinopathy Clinical Trials

77 recruitingLast updated: June 18, 2026

There are 77 actively recruiting diabetic retinopathy clinical trials across 33 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Early Phase 1, Phase 4. Top locations include Austin, Texas, United States, San Francisco, California, United States, Lakeland, Florida, United States. Updated daily from ClinicalTrials.gov.


Diabetic Retinopathy Trials at a Glance

77 actively recruiting trials for diabetic retinopathy are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 29 trials, with the heaviest enrollment activity in Austin, San Francisco, and Lakeland. Lead sponsors running diabetic retinopathy studies include University of California, San Francisco, CHU de Reims, and Association for Innovation and Biomedical Research on Light and Image.

Browse diabetic retinopathy trials by phase

Treatments under study

About Diabetic Retinopathy Clinical Trials

Looking for clinical trials for Diabetic Retinopathy? There are currently 56 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Diabetic Retinopathy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Diabetic Retinopathy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 77 trials

Recruiting
Not Applicable

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

Diabetic RetinopathyHypertension,EssentialRetinal Vein Occlusion+1 more
Johns Hopkins University1,050 enrolled1 locationNCT04505618
Recruiting

Biomarker of Diabetic Retinopathy

Diabetic Retinopathy
Indiana University192 enrolled3 locationsNCT05079399
Recruiting
Phase 2Phase 3

Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

Diabetic Retinopathy
AbbVie576 enrolled6 locationsNCT07592273
Recruiting
Not Applicable

Village-Integrated Eye Worker Trial II

Age-Related Macular DegenerationDiabetic RetinopathyGlaucoma
University of California, San Francisco60,200 enrolled1 locationNCT03752840
Recruiting

National Eye Institute Biorepository for Retinal Diseases

Age-Related Macular DegenerationDiabetic RetinopathyRetinal Disease+2 more
National Eye Institute (NEI)650 enrolled1 locationNCT01496625
Recruiting
Phase 4

To Evaluate the Efficacy and Safety of N-acetyl Cysteine Administration in Patients With Diabetic Retinopathy

Diabetic Retinopathy (DR)
Ain Shams University76 enrolled2 locationsNCT07634991
Recruiting
Not Applicable

Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal Detachment

Age related macular degeneration (AMD)Diabetic Retinopathy (DR)Retinal Detachment
Fondazione G.B. Bietti, IRCCS260 enrolled1 locationNCT07500324
Recruiting
Phase 3

Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

Proliferative Diabetic Retinopathy (PDR)
Jaeb Center for Health Research426 enrolled27 locationsNCT06790784
Recruiting
Not Applicable

Video-based Patient Education Intervention for Diabetic Eye Screening in Latinx Communities

Diabetic Retinopathy
University of Wisconsin, Madison1,526 enrolled1 locationNCT06257082
Recruiting
Not Applicable

Early Vitrectomy vs PRP in Early Proliferative Diabetic Retinopathy

Proliferative Diabetic Retinopathy (PDR)
Xiamen Ophthalmology Center Affiliated to Xiamen University100 enrolled6 locationsNCT07586787
Recruiting
Not Applicable

Soluble Cluster of Differentiation 160 (sCD160) in Sera and Intra-ocular Fluids: Association With Ischaemic Retinopathies

Diabetic RetinopathyRetinal Vein Occlusion
CHU de Reims120 enrolled1 locationNCT03680794
Recruiting
Not Applicable

Strategies for Improving Linkage-to-Care After Eye Disease Screening

Age-Related Macular DegenerationDiabetic RetinopathyGlaucoma
University of California, San Francisco3,000 enrolled1 locationNCT06943599
Recruiting
Not Applicable

Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice

Age-Related Macular DegenerationDiabetic RetinopathyCataract+2 more
University of Copenhagen460 enrolled2 locationsNCT07015034
Recruiting

Optimization and Evaluation of the Diagnosis and Treatment System for Diabetic Retinopathy in Type 2 Diabetes Mellitus

DiabetesType 2 Diabetes Mellitus (T2DM)Diabetic Retinopathy
Yufan Wang2,920 enrolled3 locationsNCT06821399
Recruiting
Not Applicable

Defining Retinal Structures Using Hyperspectral Retinal Imaging

Retinal diseasesHealthy VolunteersAge-Related Macular Degeneration+2 more
Center for Eye Research Australia1,000 enrolled1 locationNCT07555574
Recruiting
Phase 2

Sleep, Diabetic Retinopathy and Melatonin

Diabetes MellitusDiabetic Retinopathy
University of Illinois at Chicago42 enrolled1 locationNCT04547439
Recruiting
Not Applicable

Clinical Efficacy of Implementing an AI-SaMD for Funduscopy Analysis in Patients With Diabetes Mellitus

Diabetic Retinopathy (DR)Diabete MellitusFundus Photography
VUNO Inc.340 enrolled1 locationNCT07378956
Recruiting
Not Applicable

Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center

Diabetic Retinopathy (DR)Macular Edema (ME)
University of California, San Francisco150 enrolled1 locationNCT07519707
Recruiting
Not Applicable

Biomarkers in Diabetic Retinopathy Treated With Faricimab vs Biosimilar Ranibizumab

Diabetic Retinopathy (DR)Diabetic Macular Edema (DME)
Osijek University Hospital100 enrolled1 locationNCT07520045
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of OTX-TKI (Axitinib Implant) in Participants With Non-Proliferative Diabetic Retinopathy

Non-Proliferative Diabetic Retinopathy
Ocular Therapeutix, Inc.930 enrolled1 locationNCT07235085