RecruitingNot ApplicableNCT04505618

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease


Sponsor

Johns Hopkins University

Enrollment

1,050 participants

Start Date

Oct 1, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic imaging criteria that signify change in disease stage. This includes disease progression in early stages of disease or disease regression with appropriate standard-of-care treatment.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This study uses a specialized eye imaging technique called optical coherence tomography angiography (OCTA) — a non-invasive scan that shows blood flow in the retina — to study retinal vascular diseases (conditions affecting blood vessels in the eye). It compares people with eye conditions to healthy individuals. **You may be eligible if...** - You have a retinal vascular disease (such as diabetic retinopathy or retinal vein occlusion) - Or you are a healthy volunteer with no significant eye conditions - You are 18 or older - You are able to cooperate with eye imaging tests **You may NOT be eligible if...** - You are under 18, pregnant, or have developmental delays - You have a history of glaucoma or age-related macular degeneration - You have had significant eye surgery or trauma - Your eye images have poor quality (motion artifact or low signal) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICESwept-Source (SS) OCT Angiography

Non-invasive, minimal risk, ocular imaging study

DEVICESpectral-Domain (SD) OCT Angiography

Non-invasive, minimal risk, ocular imaging study

DEVICEFundus Imaging

Non-invasive, minimal risk, ocular imaging study

DEVICEAxial Length Measurement Device

Non-invasive, minimal risk, ocular imaging study


Locations(1)

Wilmer Eye Institute

Baltimore, Maryland, United States

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NCT04505618


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